Histopathology of Preclinical Toxicity Studies - Peter Greaves

Histopathology of Preclinical Toxicity Studies

Interpretation and Relevance in Drug Safety Evaluation

(Autor)

Buch | Hardcover
960 Seiten
2007 | 3rd edition
Elsevier Science Ltd (Verlag)
978-0-444-52771-4 (ISBN)
149,60 inkl. MwSt
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Covers various aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. This work relates to the preclinical safety assessment of new medicines. It also covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies.
This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.

MBChB, FRCPath, Consulting Pathologist and Honorary Senior Lecturer, Department of Cancer Studies and Molecular Medicine, University of Leicester, UK

Chapter 1: Introduction

Chapter 2: Integumentary System

Chapter 3: Mammary Gland

Chapter 4: Haemopoietic and Lymphatic Systems

Chapter 5: Musculoskeletal System

Chapter 6: Respiratory Tract

Chapter 7: Cardiovascular System

Chapter 8: Digestive System

Chapter 9: Liver and Pancreas

Chapter 10: Urinary Tract

Chapter 11: Male Genital Tract

Chapter 12: Female Genital Tract

Chapter 13: Endocrine Glands

Chapter 14: Nervous System and Special Sense Organs

Subject Index

Erscheint lt. Verlag 23.2.2007
Verlagsort Oxford
Sprache englisch
Maße 165 x 240 mm
Gewicht 10 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Laboratoriumsmedizin
Studium 2. Studienabschnitt (Klinik) Pathologie
Studium 2. Studienabschnitt (Klinik) Pharmakologie / Toxikologie
ISBN-10 0-444-52771-0 / 0444527710
ISBN-13 978-0-444-52771-4 / 9780444527714
Zustand Neuware
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