Immunology of Fungal Infections -

Immunology of Fungal Infections

Buch | Hardcover
492 Seiten
2007
Springer-Verlag New York Inc.
978-1-4020-5491-4 (ISBN)
246,09 inkl. MwSt
The history of mankind has been shaped by infections, more than by war and famine together. At the same time, however, the development of society has had an equally important effect on human diseases. The emergence of agriculture, urban societies and high population densities has been proven to be crucial for the spread of pathogens, and thus human action is currently the single most important driver of infectious epidemiology. Even today, where once major killers such as poliomyelitis have been eradicated, new pathogens are appearing as result of human activity. One such group of pathogens are the fungi, whose emergence is mainly due to modern medical practices. Fungal microorganisms, from yeasts colonizing the skin or mucosa, to molds from soil or water, are usually harmless in the context of normal host responses. However, the success of chemotherapy, as well as the AIDS pandemia, has led to immune deficiencies in a significant segment of the patient population, and the extensive use of intravenous catheters has provided a way of access for microorganisms which otherwise would find difficult to infect the host. As a result, a yeast such as Candida is now on the 4th place on the list of the most frequent sepsis agents, whereas infection with the mold Aspergillus is increasing in incidence and it is one of the most feared complications in patients with hematological malignancies.

Preface





Section 1: Cells


chapter 1: Macrophages


Sigrid E.M. Heinsbroek and Siamon Gordon; University of Oxford


chapter 2: Dendritic cells


Luigina Romani; University of Perugia


chapter 3: The neutrophil


David H. Dockrell, Emmet E. McGrath, Moira KB Whyte, and Ian Sabroe; University of Sheffield


chapter 4: Lymphocytes


Anna Vecchiarelli, Antonella Mencacci, Francesco Bistoni ; University of Perugia


chapter 5: Other cells: The role of non-neutrophilic granulocytes, NK and NKT cells in fungal immunology


Jeremy CD Wiseman and Christopher H. Mody; University of Calgary


chapter 6: Genes and gene pathways in Candida Infection


Robert B. Ashman, Camile S. Fara, and Christine Wells; University of Queensland and Griffith University





Section 2: Soluble factors


chapter 7: Collectins and pentraxins


Uday Kishore and Ken Reid; University of Oxford and Justus-Liebig-University


chapter 8: Complement in fungal infections and complement evasion strategies


Cornelia Speth, Cornelia Lass-Flörl and Reinhard Würzner; Innsbruck Medical University and Ludwig-Boltzmann-Institute of AIDS Research.


chapter 9: Cytokines


Karen F. Buckland and Cory M. Hogaboam; University of Michigan Medical School.


chapter 10: Antibodies


Josè Lòpez-Ribot, Rosalìa Dìez-Orejas and Concha Gil ; The University of Texas at San Antonio and Complutense University





Section 3: Non-Opsonic Fungal Receptors


chapter 11: The recognition of fungal pathogens by Toll-like receptors


Mihai G. Netea, Jos WM Van der Meer, Bart Jan Kullberg; Radboud University Nijmegen Medical Center and Nijmegen University Center for Infectious Diseases


chapter 12: Fungal ß-glucans and their receptors


S Vicky Tsoni and Gordon D Brown; University of Cape Town


chapter 13: Detection of fungi by mannose-basedrecognition receptors


F Meyer-Wentrup, A Cambi, CG Figdor and GJ Adema; Radboud University Nijmegen Medical Center





Section 4: Immunity to specific pathogens


chapter 14: Pneumocystis


Laura McKinley and Chad Steele, University of Pittsburgh School of Medicine


chapter 15: Interactions of Aspergillus fumigatus with its host during invasive pulmonary infections


Jean-Paul Latgé and Anne Beauvais; Pasteur Institute


chapter 16: C. albicans and C. glabrata


Desa Lilic and Ken Haynes, School of Clinial Medicines, Newcastle University and Department of INfectious diseases, Imerpial College London


chapter 17: Immunology of infections with Cryptococcus neoformans


Pauline Ellerbroek, Anna Vecchiarelli, Andy Hoepelman and Frank Coenjaerts; University Medical Center and University of Perugia.


chapter 18: Histoplasma capsulatum


Joshua D Nosanchuk; Albert Einstein College of Medicine





Section 5
chapter 19: Escape mechanisms from the immune response


David M. Underhill; Cedars-Sinai Medical Center





Section 6: Immune-based therapeutic strategies


chapter 20: Cytokine treatment of fungal infections


Bart-Jan Kullberg; Radboud University Nijmegen Medical Center


chapter 21: Fungal vaccines and vaccination: problems and perspectives


Antonio Cassone; Istituto Superiore di Santià





Index

Zusatzinfo XVIII, 492 p.
Verlagsort New York, NY
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Studium Querschnittsbereiche Infektiologie / Immunologie
ISBN-10 1-4020-5491-2 / 1402054912
ISBN-13 978-1-4020-5491-4 / 9781402054914
Zustand Neuware
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