Transport in the Liver

Preface. Section I: Concepts in Hepatic Transport. 1. Mechanisms in membrane transport; G. Burckhardt. 2. Physiological utility of biliary secretion and excretion; A.F. Hofmann. 3. Regulation of transport across hepatocyte membranes -- determinants of bile formation; J.L. Boyer. 4. Molecular properties of two basolateral bile acid and organic anion transporters of rat and human liver; P.J. Meier, B. Hagenbuch, B. Stieger, G. Kullak-Ublick, E. Jacquemin. Section II: Uptake Across the Hepatocyte Sinusoidal Membrane. 5. Molecular cloning and expression of a human cDNA encoding system ASC amino acid transport activity; M.S. Kilberg, B.K. Tamarappoo, S. Shafgat, R.T. Fremeau Jr. 6. Glucose transport across hepatic membranes; A. Burchell. 7. Mechanism of cellular fatty acid uptake: a 1994 update; W. Stremmel, B.A. Fitscher, C. Elsing, U. Winn-Börner, J. Gunawan, H. Kleinert, K. Vogelsang, A. Kassner, K. Möller, M. Schürer. 8. Transport of conjugated and unconjugated bile salts across the sinusoidal membrane; W. Gerok, G. Kurz, D. Schwab. Section III: Intracellular Events in Conjugation and Transport. 9. Cellular hydration and bile acid secretion in the isolated perfused rat liver; D. Häussinger. 10. Intracellular vesicles and the transport of organic anions; R.P.J. Oude Elferink, H. Roelofsen, C. Bakker, R. Ottenhoff, M. Heijn. 11. A transport system for glutathione in rat liver endoplasmic reticulum; H.-D. Söling, A. Weilandt, A. Wasmuth. 12. Hepatic glutathione conjugation and membrane-bound glutathione S-transferase activities; T.P.M. Akerboom, M.E. Horbach, H. Sies. Section IV: Transport Across the Hepatocyte Canalicular Membrane. 13. Canalicular ecto-ATPase and ATP-dependent transport; I.M. Arias, D. Ortiz, C. Leveille-Webster, M. Che, M. St-Pierre, J.F. Dufour, Z. Gatmaitan. 14. ATP-dependent transport of amphiphilic cations across the canalicular membrane mediated by P-glycoprotein; M. Muller. 15. Mechanisms of canalicular GSH secretion; N. Kaplowitz, J.C. Fernández-Checa, J-R Yi. 16. Expression of canalicular bile salt transporters; F.J. Suchy. 17. Cholestasis resulting from inhibition of the ATP-dependent bile salt export carrier by cyclosporins; M. Böhme, I. Leier, G. Jedlitschky, D. Keppler. 18. Mechanisms of intrahepatic cholestasis; H. Takikawa, N. Sano, Y. Wako, M. Fujiyoshi, M. Yamanaka. Section V: Multidrug Resistance Gene Products and ATP-Dependent Transport Across the Canalicular Membrane. 19. Structure and function of P-glycoprotein transporter; M.M. Gottesman. 20. The physiological role of mdr2 P-glycoprotein in hepatobiliary phospholipid transport; R.P.J. Oude Elferink, J.J.M. Smit, A.H. Schinkel, R. Ottenhoff, M. van Wijland, G.J.A. Offerhaus, P. Borst, A.K. Groen. 21. Regulation of the multidrug resistance genes in the rat liver; J.A. Silverman, B.A. Hill, P.A. Brown, K.H. Preisegger, T.W. Gant. 22. Substrates for P-glycoprotein in kidney; R. Hori, Y. Tanigawara, M. Hirai, M. Yasuhara, K. Ueda, T. Komano. 23. P-glycoprotein expression in normal and transformed hepatocyte cultures; O. Fardel, V. Lecureur, A. Guillouzo. 24. Induction of multidrug resistance gene products in cholestasis; D. Schrenk, T.W. Gant, H.-H. Preisegger, J.A. Silverman, S.S. Thorgeirsson. Index.