Transfusion Microbiology -

Transfusion Microbiology

Buch | Hardcover
410 Seiten
2008
Cambridge University Press (Verlag)
978-0-521-45393-6 (ISBN)
145,90 inkl. MwSt
It is critical that blood transfusion poses as low a risk as possible. Many pathogens can be transmitted by transfusion, and testing is complex and costly. This text covers all infective agents, donor selection and blood testing. Quality, regulation, cost benefit and risk assessment issues are also reviewed.
Extensive measures are taken to ensure that blood transfusion poses a minimal microbiological hazard to recipients. Transfusion Microbiology is the definitive text on all aspects of transfusion transmitted infections. This comprehensive text covers all medical, scientific, technical and developmental aspects of this critically important sector of transfusion medicine. A detailed discussion of all infective agents, donor issues, testing and pathogen inactivation is provided. Agents causing major concern recently, such as vCJD, are considered in the context of historical experience with agents such as HIV. All aspects of risk assessment, regulation, cost benefit analysis and quality management are reviewed. Relevant to blood transfusion centres, hospital transfusion laboratories, haematologists and microbiologists, medical, scientific and technical staff, universities and general training programmes worldwide, Transfusion Microbiology provides an up-to-date resource for all practitioners and researchers involved in transfusion medicine.

John A. J. Barbara is an Emeritus Consultant in Microbiology to the National Blood Service in England and the Visiting Professor in Transfusion Microbiology at the University of West England, Bristol, UK. Fiona A. M. Regan is a Consultant Haematologist at NHSBT and Hammersmith Hospitals NHS Trust, London, UK. Marcela C. Conteras is a Visiting Professor of Transfusion Medicine in the Faculty of Applied Sciences at the University of West England, Bristol, UK. She was formerly the National Director of Diagnostics, Development and Research at the National Blood Service. She was awarded a DBE in 2007 for her services to healthcare.

Foreword Roger Y. Dodd; Preface; Acknowledgements; Glossary; Introduction John A. Barbara, Roger Eglin; Part I. Agents: 1. Hepatitis viruses Denis M. Dwyre and Paul V. Holland; 2. Anti-HBc Joan O'Riordan; 3. Herpes viruses Eleftherios C. Vamvaka and Gary E. Tegtmeier; 4. Retroviruses Brian C. Dow, E. W. Fiebig and Michael P. Busch; 5. Parvovirus B19 (human erythroviruses) Kevin E. Brown; 6. Emerging viruses in transfusion Jean-Pierre Allain; 7. Bacterial contamination in blood and blood components Carl P. McDonald and M. A. Blajchman; Annexe, Syphilis Brian C. Dow; 8. The protozoan parasites David A. Leiby and Silvano Wendel; 9. Prion diseases Marc L. Turner, Patricia E. Hewitt, Moira Bruce and James W. Ironside; Annexe, Testing for prions David Anstee and Gary Mallinson; Part II. Selection and Testing: 10. Blood donor selection and qualification Virge James; 11. Current serological methods of testing and automation Peter D. Rogan; 12. Confirmatory testing and donor readmission Alan D. Kitchen and Brian C. Dow; 13. The strategy for applications of nucleic acid testing Paul R. Grant and Richard S. Tedder; 14. Nucleic acid testing, general view W. Kurt Roth; 15. Nucleic acid testing, the US approach Susan L. Stramer; 16. Nucleic acid testing, the English approach Roger Eglin; 17. Quality in the screening of donations for transfusion transmissible infections Alan D. Kitchen and John A. Barbara; 18. Microbiological blood testing and new technologies Juraj Petrik; 19. Processing and components, Leucodepletion and pathogen reduction Rebecca Cardigan, Chris Prowse and Lorna M. Williamson; 20. Fractionated products Peter R. Foster and Carol Bienek; Part III. Surveillance, Risk and Regulation: 21. Serious hazards of transfusion (SHOT), Haemovigilance Elizabeth M. Love; 22. Investigation of post transfusion infection Patricia E. Hewitt and Chris Moore; 23. Notification of donors with significant microbiological test results Patricia E. Hewitt and Chris Moore; 24. Researching the natural history of transfusion transmitted infections, the UK hepatitis C national register Helen Harris; 25. How to assess risk, prospective studies and calculations Kate Soldan and Katy Davison; 26. Risk management Arturo Pereira; 27. The regulatory environment in Europe Virge James; 28. Blood safety in developing countries Jean-Pierre Allain, Elizabeth Vinelli and Yasmin Ayob; Index.

Erscheint lt. Verlag 24.4.2008
Zusatzinfo 2 Plates, color; 50 Halftones, unspecified; 48 Line drawings, unspecified
Verlagsort Cambridge
Sprache englisch
Maße 220 x 280 mm
Gewicht 1670 g
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
ISBN-10 0-521-45393-3 / 0521453933
ISBN-13 978-0-521-45393-6 / 9780521453936
Zustand Neuware
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