TOXICOLOGY LUNG

Methodologies and technology for animal inhalation toxicology studies; nasal structure, function, and toxicology; gross morphometry of airways; cell populations and structure-function relationships of cells in the airways; morphometric analysis of the gas exchange region of the lung; three- dimensional analysis of lung structure and its application to pulmonary Dosimetry Models; Metabolism Of Xenobiotics The Respiratory Tract; extrapolation of animal data to humans - homology of pulmonary physiological responses with ozone exposure; biological markers of respiratory tract exposure; quantitative clinical studies with defined exposure atmospheres; the epidemiologic approach to investigating indoor and outdoor air pollution; cellular approaches in respiratory tract toxicology; pulmonary reactions and mechanisms of toxicity of inhaled fibres; immunological responses within the lung after inhalation of airborne chemicals; chemically-induced pulmonary hypersensitivity, airway hyperactivity and asthma; chronic inhalation bioassays for respiratory tract carcinogenesis; advances in physiological modelling approaches for understanding the disposition of inhaled vapours; regional respiratory tract absorption of inhaled reactive gases; approaches to modelling disposition of inhaled particles and fibres in the lung; developing risk assessments for airborne materials.