Thrombolytic Therapy in Acute Ischemic Stroke

I. Acute Cerebral Ischemia and Thrombolysis.- Natural History of Atherothromboembolic Occlusion of Cerebral Arteries: Carotid Versus Vertebrobasilar Territories.- Fibrinolysis: Thrombolytic Agents, Mechanisms, and New Developments.- Fibrinolysis in Myocardial Infarction: Lessons for Cerebrovascular Disease.- Reperfusion of Ischemic Brain: Why and Why Not!.- Thrombolysis in Stroke: Timing of Recanalization and Its Clinical Consequences.- The Ischemic Penumbra: Fact or Fiction?.- Hemorrhagic Transformation in the Natural History of Acute Embolic Stroke.- Intracranial Hemorrhage After Coronary Thrombolysis with Tissue Plasminogen Activator.- Predictive Factors for the Effective Treatment of Acute Stroke with Intravenous Thrombolytic Agents.- Invasive Imaging Techniques in the Evaluation of Patient Selection and Cerebrovascular Recanalization.- The Role of Noninvasive Imaging Techniques in Cerebrovascular Recanalization.- II. Thrombolysis and Stroke Models.- Thrombolytic Therapy in Ischemic Stroke: Relevance and Limitations of Animal Models.- Update on Animal Model Experience with Recombinant Tissue Plasminogen Activator.- III. Clinical Trials.- Clinical Trials: Some General Considerations.- Intraarterial Urokinase Plasminogen Activator and Streptokinase in Carotid and Vertebrobasilar Territory Stroke: Clinical Outcome.- Fibrinolytic Recanalization Therapy in Acute Cerebrovascular Thromboembolism.- Intravenous Recombinant Tissue Plasminogen Activator in Acute Thrombotic Stroke: Study Design, Recanalization, and Clinical Outcome.- Evaluation of Tissue Plasminogen Activator Early in the Course of Acute Ischemic Stroke.- Intravenous Recombinant Tissue Plasminogen Activator in Acute Stroke.- Thrombolytic Therapy in Embolic and Thrombotic Cerebral Infarction: A Cooperative Study.- IV. Future Directions.- Problems in Formulating Therapeutic Trials.- Invasive and Noninvasive Vascular Imaging Techniques and Their Role in Clinical Stroke Trials.- Strategies for Early Treatment of Acute Cerebral Infarction.- V. Open Communications.- Topical Intraarterial Urokinase Infusion for Acute Stroke.- Local Thrombolytic Therapy in Acute Basilar Artery Occlusion: Experience with 18 Patients.- Vertebrobasilar Occlusion: Outcome With and Without Local Intraarterial Fibrinolysis.- Recanalization of Acute Middle Cerebral Artery Occlusion Monitored by Transcranial Doppler Sonography.- Neuropathological Findings After Thrombolytic Therapy in Acute Ischemic Stroke.- How Many Stroke Patients Are Candidates for Thrombolysis?.- Spontaneous Recanalization in Middle Cerebral Artery Occlusion.- In Vitro Thrombus Lysis by Urokinase in Preparation for Patient Studies.- Local Intraarterial Fibrinolysis in Acute Middle Cerebral Artery Occlusion.- Treatment of Acute Ischemic Stroke with Recombinant Tissue Plasminogen Activator: Evaluation with Regional Cerebral Blood Flow Single Photon Emission Computed Tomography.- Thrombolytic Therapy in Acute Ischemic Stroke: The Copenhagen Multicenter Study.- Thrombolytic Therapy in Cerebral Sinus Thrombosis: A Case Report.- Basilar Artery Occlusion Associated with Protein C Deficiency: Successful Treatment Using Recombinant Tissue Plasminogen Activator Infusion.- Intracerebral Hemorrhage and Infarction Volume Following Recombinant Tissue Plasminogen Activator in an Acute Stroke Model.- Prourokinase Therapy in Stroke.