Teratogenic Effects of Drugs

Containing over 9000 entries and an index list of 34,000 synonyms, this book offers clinically-orientated information on the potential teratogenic effects of drugs and other agents on the developing foetus or embryo. A rating system is used to assess the risk associated with exposure to each agent.

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"A teratogen", write the authors, "may be defined as an agent that can produce a permanent abnormality of structure or function in an organism exposed during embryonic or foetal life". Although the number of individuals affected by such agents is relatively small - perhaps accounting for as few as one-tenth of all birth defects - they are nevertheless significant because each case is potentially preventable. "Teratogenic Effects of Drugs" presents a catalogue of teratogenic agents which is intended for use by clinicians. With more than 9000 entries and an extensive index list of 34,000 synonyms, the book offers clinically-orientated information on the potential teratogenic effects of drugs and other agents on the developing foetus or embryo. A rating system is used, by which an internationally recognized panel of teratologists assesses the risk associated with usual exposures to each agent. Also rated is the quality and quantity of data upon which the panel's assessment is based. Each entry includes a concise clinical narrative summary that reviews the available information as well as a list of key references.
"Teratogenic Effects of Drugs" is the hardcover version of a computerized database known as TERIS, the on-line version of which first appeared in 1987.