Für diesen Artikel ist leider kein Bild verfügbar.

The SV40 Replicon Model for Analysis of Anticancer Drugs

Buch | Hardcover
200 Seiten
1996
Academic Press Inc (Verlag)
978-0-12-653630-0 (ISBN)
108,45 inkl. MwSt
Provides a review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. This book focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. It covers the high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication.
This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments.

Dr. Snapka is an associate professor of Radiology at The Ohio State University, teaching courses in Radiation Biology, DNA Tumor Viruses, Drug Resistance, and Genetic Instability. Dr. Snapka earned his B.S. in Biology and M.S. in Chemistry at North Texas State University. He earned his Ph.D. at the University of California, Irvine and worked as a Research Fellow at the University of California, Berkeley and Massachusetts Institute of Technology. He is the author of over 35 article in refereed journals and is currently conducting research in anticancer drug resistance and drug discovery.

R.M. Snapka, Papovavirus Models for Mammalian Replicons.R.M. Snapka, Analysis of SV40 DNA Replication Intermediates.R.M. Snapka, Catastrophic Failure of DNA Replication Forks: Structural and RecombinationalPathways.R.M. Snapka and E.F. Yamasaki, Topoisomerase II and the Termination of DNA Replication.R.M. Snapka, DNA Damaging Agents.R.M. Snapka, C.A. Ferrar, N.-J. Sun, and J.M. Cassady, Drug Discovery and Evaluation with SV40.L.H. Malkas, Simian Virus 40 (SV40) in Vitro DNA Replication: A Potential Model for Studying Anticancer Drug Action.R.M. Snapka and P.A. Permana, SV40 Circular Oligomer Series: Normal and Abnormal DNA Replication.Subject Index.

Erscheint lt. Verlag 23.5.1996
Reihe/Serie Biotechnology Intelligence Unit
Verlagsort San Diego
Sprache englisch
Maße 182 x 257 mm
Gewicht 730 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Onkologie
Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Studium 2. Studienabschnitt (Klinik) Humangenetik
ISBN-10 0-12-653630-9 / 0126536309
ISBN-13 978-0-12-653630-0 / 9780126536300
Zustand Neuware
Haben Sie eine Frage zum Produkt?
Mehr entdecken
aus dem Bereich
Eine sehr persönliche Geschichte | Der New York Times-Bestseller

von Siddhartha Mukherjee

Buch | Softcover (2023)
Ullstein Taschenbuch Verlag
21,99
Die revolutionäre Medizin von morgen (Lifespan)

von David A. Sinclair; Matthew D. LaPlante

Buch | Softcover (2020)
DuMont Buchverlag
16,00