Surfactant Therapy for Lung Disease

Basic Physiological and Biochemical Aspects of Surfactant Function

Biophysical Aspects in the Design of a Therapeutic Surfactant, Samuel Schurch and Hans Bachofen
Surfactant and Lung Fluid Balance, David P. Carlton and Richard D. Bland
Biosynthesis, Secretion, and Recycling of Surfactant Components, Joseph J. Batenberg
Pulmonary Surfactant and Lung Defense: Interactions of Surfactant Proteins with Phagocytic Cells and Pathogens, J. Freek van Iwaarden and Lambert M.G. van Golde

Pathology and Clinical Diagnosis of Surfactant Dysfunction

Genetics of Neonatal Lung Disease in Relation to the Surfactant Protein Genes, Joanna Floros and Anne M. Karinch
A Stable Microbubble Test for Antenatal and Early Neonatal Diagnosis of Surfactant Deficiency, Shoichi Chida
Lung Mechanics in Respiratory Distress Syndrome, Robert B. Cotton and Torsten Olsson
Radiological Diagnosis of Neonatal Respiratory Distress Syndrome and Related Disorders, William H. Northway, Jr.
The Adult Respiratory Distress Syndrome: Pathophysiological Concepts Related to the Pulmonary Surfactant System, Ulrich Pison, Johannes C. Bock, Sylvia Pietschmann, Siegfried Veit, and Klaus Slama
Evaluation of Lung Permeability in Neonatal and Adult Respiratory Distress Syndrome, Per Wollmer, Bjorn Johnson, and Burkhard Lachmann

Pharmacology of Exogeneous Surfactant

Essential and Nonessential Constituents of Exogenous Surfactants, Pinar Bonuck-Dayanikli, and H. William Taeusch
Experimental Models for Evaluation of Exogenous Surfactants, Bengt Robertson
Resistance to Surfactant Inactivation, Andreas Gunther and Werner Seeger
Antigenicity of Surfactant Proteins A, B, and C, Timothy E. Weaver and Jeffrey A. Whitsett

Clinical Use of Surfactant for Prevention and Treatment of Lung Disease

Techniques for Administering Surfactant, Alan H. Jobe
Biochemical Prediction of Response to Surfactant Therapy in the Newborn Infant, Mikko Hallman, Jack Sills, Kristina Bry, and T. Allen Merritt
Prediction of Mechanical Responses to Surfactant Therapy, Jon Goerke
Augmentation of Exogenous Surfactant Treatments with Lung Maturational Agents, Steven R. Seidner
Clinical Trials of Surfactant Therapy in the Newborn, Roger F. Soll
Treatment Strategies for Surfactant Therapy in Established Neonatal Respiratory Distress Syndrome, Henry L. Halliday and Christian P. Speer
Surfactant Therapy for Neonatal Lung Disorders Other Than Respiratory Distress Syndrome, Frans J. Walther
Effects of Surfactant Replacement on Lung Mechanics, Nils W. Svenningsen
Ventilation Strategies in Relation to Surfactant Replacement, Robert A. deLemos, Rangasamy Ramanathan, and Jacqueline J. Coalson
Radiographic Evaluation of the Therapeutic Response, David K. Edwards III
Cardiovascular Effect of Surfactant Replacement with Special Reference to the Patent Ductus Arteriosus, Gad Alpan and Ronald I. Clyman
Effects of Surfactant Replacement on Cerebral Hemodynamics and Oxygenation, E.O.R. Reynolds, A.D. Edwards, and D.C. McCormick
Reoxygenation Effects of Surfactant Replacement Therapy, Ola Didrik Saugstad
Surfactant Therapy for Adult Respiratory Distress Syndrome, Francis X. McCormack and Robert J. Mason
Outcomes of Surfactant-Treated Infants: Analysis of Developmental Outcome and the Economic Impact of Surfactant Therapy, T. Allen Merritt, Yvonne Vaucher, Terry Turner, and Mikko Hallman
Postscript: Perspectives for the Future, Bengt Robertson and H. William Taeusch