From Genes to Phenotypes

Preface; Basic Mechanisms; * Allergy is in the Blood at Birth; * Interleukin-4/13-Induced Activation of STAT 6 is Regulated by SOCS; * Th1-Mediated Inflammation as a Potential Pathogenic Factor in Allergic Disease; * Healthy or Allergic Immune Response Characterized by Fine Balance Between Specific T Regulatory 1 and T Helper 2 Cells; * Indications for the Existence of an IgE Isotype - Specific Signal Transduction; * Differential Expression of IgA-Positive Plasma Cells in Palatine Tonsils of Bet v 1-Allergic Patients and Healthy Individuals; * Survivin - A Key Regulator of Neutrophil and Eosinophil Survival; * Expression of CD8-a on Human Monocytes and Alveolar Macrophages; * Autoimmunity and Allergy: A Bioinformatic Approach; Dendritic Cells; * Dendritic Cells and Regulatory T-Cells in the Allergic Immune Response and its Modulation; * Expression of High Affinity IgE Receptors on Skin- and Blood-Derived Plasmacytoid Dendritic Cells in Inflammatory Skin Diseases; * M-DC8 Dendritic Cells as Potent Inducers of Th1 Polarized Immune Responses; * Characteristics of Plasmacytoid Dendritic Cells in Patients with Atopic Dermatitis; Mast Cells; * Activation of SPHK 1 in Mast Cells by Tyrosine Kinase Lyn; * Comparative Database for Transcriptomes of Human and Mouse Inflammatory Cells; * Mast Cell Inhibition by a2-Adrenoceptor Agonists; * Effects of Cannabinoid Agonists on Histamine Release from Activated Human Skin Mast Cells; * Expression and Function of Inhibitory and Activatory Receptors on Mast Cells and Eosinophils: New Mechanisms in Mast Cell-Eosinophil Crosstalk; * Relaxin Inhibits Activation of Human Neutrophils in vitro by a Nitric-Oxide-Dependent Mechanism; Allergens; * Cloning, Expression, Characterization, and Skin Prick Testing of NADPH-Dependent Mannitol Dehydrogenase: A New Major Allergen of Cladosporium herbarum; * Cosensitization to Cockroach and Mite Is Not Explained by Tropomyosin Cross-Reactivity; * Can Chinese Elm Pollen Cause Asthma?; * Inhalation Allergy and Desensitization to a Cysteine Protease Allergen; * Apple Allergy: Different Patient Allergen Recognition Patterns Across Europe, Studied by Use of Recombinant Allergens; * Intracellular Targeting: A New Concept for the Development of Efficient Vaccines; * The Molecular Requirements for Allergenicity; Infection and Allergy; * Peroxisome Proliferator-Activated Receptor [gamma] Ligands Have Antiviral and Anti-Inflammatory Activity in the Course of Respiratory Syncytial Virus Infection; * Differences in Bifidobacterium Species in Early Infancy and Development of Allergy; * Comparison of Expression and Function of Toll-Like Receptors in Eosinophils and Neutrophils; * Human T-Cells of Atopic and Nonatopic Donors Are Activated by Staphylococcal [alpha]-Toxin; Skin, Nerves, and Allergy; * Increased Apoptosis of Circulating Memory/Effector Th1 Cells in Atopic Diseases as Mechanism for Th2 Predominance; * Reduced Number of Cytokine-Expressing Inflammatory Cells in AD After Topical Tacrolimus Treatment; * New Methods for Quantitative and Qualitative Assessment of Itch; * Expression of Two Neuropeptide Receptors, Calcitonin-Gene-Related Peptide, and Somatostatin in Peripheral Blood Mononuclear Cells from Patients with Atopic Dermatitis and Nonatopic Controls; * The Influence of Neuropeptides on Cytokine Production in Peripheral TCells in Atopic Dermatitis Patients with Acute and Chronic Lesions and in Controls; * Eotaxin-1 SNP Associations in Allergic Conjunctivitis; * Neurotrophins in Allergic Bronchial Asthma: Modulators of Immunological and Neuronal Plasticity; * Neuroimmunological Crosstalk in Atopic Dermatitis: Critical Role of Neurotrophins in Eosinophil Function; Asthma; * Kinetics of Cytokine Production by Human Lung Tissue; * 21-Year Longitudinal Study of Healthy Infants Correlates with Atopy, Allergic Disease, and Asthma (The RIFYL Study; * Angiogenesis and Remodeling of Airway Vasculature in Asthma; * Protease-Activated Receptor-2 Enhances Allergen-Induced Airway Inflammation and Airway Hyperresponsiveness; * Glucocorticoids Promote T Regulatory Cells in Asthma by Increasing FOXP3 Expression; * The Phenotype of Steroid-Dependent Severe Asthma Is Not Associated with Increased Lung Levels of Th-2 Cytokines; * Bronchial Smooth Muscle Cells Apoptosis in Airway Remodeling; Food Allergy; * In vitro Methods for Monitoring the Development of Clinical Tolerance to Foods; * In vitro Methods for Assessing the Potential Severity of Food Allergic Reactions; * Eosinophilic Esophagitis: New Clinical and Pathophysiological Insights; * Histamine Release for Determination of Systemically Absorbed Allergenic Proteins in Humans; * Proton Pump Inhibitors Promote Oral Sensitization to Hazelnut; * Oral Threshold Levels and in vivo Basophil Activation in Hazelnut Allergic Patients During Oral Provocation Tests; * Digestion-Sensitive Wheat Proteins Can Induce Food Allergy; Diagnostics; * What Can We Learn from the Ratio of IgG1/IgG4 Antibodies to Allergens?; * Immunoglobulin-Free Light Chains in Immediate and Delayed Hypersensitivity Reactions; * Expression of Plasma Cell Markers CD38, CD138, Intracellular IgE, and XBP-1 in the Plasmacytoid Cell Line U266; * Improvement of the in vitro Diagnostic of Natural Rubber Latex Allergy: Estimation of Cross-Reactivity Through Application of Recombinant and Natural Single Allergens; * Hypersensitivity to NSAID Drugs: A New Integrated Approach to Its Pathophysiological Understanding and Diagnosis; * Pollen-Associated Food Allergy: In vitro Diagnosis by Recombinant Allergens and CD63 Expression of Basophils; * Immediate Adverse Reactions to Cephalosporins: Study of in vitro Crossreactivity by Determining Specific IgE to Different Betalactams; Therapy; * Anti-Interleukin-5 in the Treatment of Hypereosinophilic Skin Diseases; * Lack of Availability of Epinephrine for First-Aid Treatment of Anaphylaxis Worldwide; * A Candidate Vaccine for Specific Immunotherapy in Latex Allergy: Hypoallergenic Variants of Hev b 6.01.; * Randomized Controlled Trial of Specific Immunotherapy on Allergic Inflammation in Atopic Dermatitis Patients with Sensitization to House Dust Mites; * Allergy Prophylaxis by DNA Vaccination Inhibits Specific IgE Response and Lung Pathologic Parameters in a Mouse Model; * Quality of Life and Compliance in Patients Allergic to Grass and Rye Pollen During a 3-Year Treatment with Specific Immunotherapy (The LQC Study); * Targeting M-Cells for Induction of a Th1-Immune Response in Allergic Mice; * Successful Mucosal Immunotherapy in Asthma Induces Tolerance and M. vaccae Potentiates IL-10-Related Tolerance in a Murine Asthma Model; * Molecular Basis of the Anti-IgE Therapy; * Inhibition of IgE-Facilitated by Allergen Presentation: A Longitudinal Study of Grass-Pollen Immunotherapy.