Mass Spectrometry in Drug Metabolism
Kluwer Academic/Plenum Publishers (Verlag)
978-0-306-31018-8 (ISBN)
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Identification of Drugs and Drug Metabolites.- A study on the metabolism of feprazone utilizing mass spectrometry.- Identification of some urinary metabolites of iopronic acid in human, rat and dog.- Metabolite identification by GC-MS: species differences in the metabolic patterns of isopropylbiphenyl.- Structural elucidation of an S-oxidized metabolite of trithiozine in rat and dog.- Some metabolites of 9-hydroxy-19,20-bis-nor-prostanoic acid.- Formation of a new amino acid as a metabolic intermediate of sodium dipropylacetate.- Identification of the N-acetyl-ß-aryloxyalanines from rats treated with 3-(p-tolyloxy)-1,2-propanediol and 3-phenoxy-1,2-propanediol.- Metabolism in rat, dog and man of difenpiramide, a new anti-inflammatory drug.- Potential drugs from propolis.- Quantitation of Drugs and Drug Metabolites.- Mass fragmentography (single and multiple ion monitoring) in drug research.- Mass spectrometric identification and quantification of compounds involved in the metabolism of pyrazofurin.- Mass spectrometry applied to metabolism studies of Org GC 94, a new anti-migraine drug.- The identification and measurement in urine of dihydrodigoxin, a cardioinactive metabolite of digoxin.- Determination of dimethylnitrosamine in extracts from cultures of Trichomonas vaginalis, using gas chromatography and mass spectrometry.- Blood concentrations of monoacylcadaverines in schizophrenia.- MHPG, amitriptyline and depression: a collaborative study.- Drugs and drug metabolites as environmental contaminants: detection of chlorophenoxyisobutyrate and salicylic acid by GC-MS.- Intermediates in the Metabolism of Drugs.- Application of chemical ionization MS and the twin-ion intermediates in technique in the analysis of reactive drug metabolism.- Relationship between structure and metabolism of tricyclic drugs: stable epoxide-diol pathway.- Stable Isotope Labelling.- A study of protein metabolism in chronic-enterocolitis patients and the effect of pharmacological agents using mass spectrometry.- Biochemical applications of high precision isotope analysis by combined gas chromatography-mass spectrometry.- Developments in Methodology.- Chemical ionization mass spectrometry in the identification of drugs and drug metabolites.- Field desorption mass spectrometry of pharmacologically active salts.- Role of computers in gas chromatography-mass spectrometry: detection, identification, and quantification in drug metabolism research.- A real time gas chromatograph-mass spectrometer minicomputer system for selected ion analysis.- Drug Abuse.- Can gas chromatography - mass spectrometry influence trends in drugs abuse?.- Characterization of in vivo liver metabolites of ?1--tetrahydrocannabinol by EI and CI mass spectrometry.- Detection and quantification of cannabinoids in human blood plasma.- Identification of a major metabolite of tetrahydrocannabinol in plasma and urine from cannabis smokers.- Analysis of impurities in illicit heroin by mass spectrometry.- Screening by gas chromatography-mass spectrometry for metabolites of five commonly used anabolic steroid drugs.- Mass spectrometry in acute intoxication diagnostics: aspects and experiences.- Participants.
Erscheint lt. Verlag | 1.3.1977 |
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Zusatzinfo | XII, 532 p. |
Verlagsort | New York |
Sprache | englisch |
Gewicht | 1060 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
Medizin / Pharmazie ► Pharmazie | |
Medizin / Pharmazie ► Studium ► 1. Studienabschnitt (Vorklinik) | |
Naturwissenschaften ► Biologie ► Biochemie | |
Naturwissenschaften ► Chemie ► Analytische Chemie | |
ISBN-10 | 0-306-31018-X / 030631018X |
ISBN-13 | 978-0-306-31018-8 / 9780306310188 |
Zustand | Neuware |
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