Nuclear Medicine

VOLUME I Part I. INTRODUCTION 1.Mileposts in Nuclear Medicine History 2.Decision Making, Statistics, and Informatics 3.Radiation Safety Part II. The Scientific Basis of Nuclear Medicine A. PHYSICS 4.Basic Physics of Nuclear Medicine 5.Gas-Filled Ionization Radiation Detectors in Nuclear Medicine 6.Scintillation Detectors and Scintillation Detector Counting Systems 7.Gamma Camera Imaging Systems 8.Gamma Camera Collimator Characteristics and Design 9.Nuclear Counting Statistics 10.Progress in Semiconductor Detectors for use in Nuclear Medicine 11.Representation of Gamma Camera Images by Computer 12.Image Content and Image Filtering Techniques 13.In Vivo Quantitation of Activity by Planar Imaging 14.SPECT Image Reconstruction 15.Gamma Camera SPECT Systems and Quality Control 16.Nuclear Medicine Image Display Techniques 17.Quantitative SPECT 18.A Quality Control Program for Nuclear Medicine Cameras 19.Principles of PET and PET/CT Imaging 20.PET Image Reconstruction 21.Tracer Kinetics: Principles of Compartmental Analysis and Physiologic Modeling 22.Internal Radiation Dosimetry B. RADIOPHARMACY 23.Principles of Radiopharmacy 24.Pathway for FDA Approval of New Radiopharmaceuticals 25.Radionuclides: Cyclotron, Reactor, and Fission Products 26.Radionuclide Generators: Design, Operation, and Clinical Utility 27.The Chemistry of Technetium and Other Metals As It Applies to Radiopharmaceuticals 28.Radiopharmaceutical Chemistry: Iodination Techniques 29.Radiolabeling Formed Elements of Blood: Methods and Mechanisms 30.Quality Control in the Hot Lab 31.Ensuring Microbiologic Purity of Radiopharmaceuticals 32.Positron Radiopharmaceuticals and Their Chemistry 33.In Vivo Nonimaging Studies 34.Principles and Applications of Radioassays 35.Adverse Reactions to Radiopharmaceutical agents and Long-term Effects 36.Basic Principles of Radiation Biology 37.Planning for Radiation Accidents and Radiologic Events Part III. Immunologic Aspects of Nuclear Medicine 38.New approaches to radiolabeling monoclonal antibodies 39.Tumor necrosis therapy of cancer: new methods of antibody targeting 40.Radiation dosimetry of radiolabeled monoclonal antibodies: practical considerations 41.Overview of imaging procedures with radiolabeled monoclonal antibodies in cancer patients Part IV. Clinical Organ Systems Studies A. CARDIOVASCULAR 42.Radiopharmaceutical agents for cardiac imaging 43.Computer aspects of myocardial imaging 44.Functional cardiac imaging 45.Clinical applications of myocardial perfusion imaging 46.Radiopharmaceuticals for myocardial infarct imaging 47.MIBG imaging 48.Positron Emission Tomography of the Cardiovascular System 49.Peripheral vascular disease: arterial and venous B. ENDOCRINE 50.The thyroid gland 51.Scintigraphic imaging of the adrenals and neuroectodermal tumors 52.Parathyroid scintigraphy 53.Correlative endocrine imaging VOLUME II C. GASTROINTESTINAL 54.Radiopharmacy aspects of gastrointestinal imaging 55.Salivary glands 56.Esophageal transit and reflux gastric emptying 57.Radiopharmaceuticals for liver and spleen imaging 58.Liver and spleen imaging 59.Radiopharmaceuticals for hepatobiliary imaging 60.Hepatobiliary imaging 61.Evaluating gastrointestinal bleeding by nuclear medicine techniques 62.Scintigraphic assessment of peritoneovenous shunt function D. Genitourinary 63.Radiopharmaceuticals for renal imaging 64.Glomerular Filtration 65.The role of ACE inhibitor renography in the diagnosis of renovascular hypertension 66.Evaluation of renal transplants 67.Testicular imaging 68.Pediatric Urology E. Musculoskeletal 69.Bone Imaging Radiopharmaceuticals 70.Skeletal scintigraphy in non-neoplastic osseous disorders 71.Malignant bone disease 72.Bone marrow scintigraphy 73.Measurement and interpretation on bone mineral density F. Neurology 74.Radiopharmaceuticals for cerebral imaging 75.Cerebral perfusion imaging 76.Cerebrospinal fluid imaging 77.The role of positron emission tomography in the investigation of neurological disorders 78.The role of positron emission tomography in the investigation of psychiatric disorders 79.Correlative imaging in neurology and neurosurgery G. Pulmonary 80.Radiopharmaceuticals for pulmonary imaging 81.Ventilation/perfusion scintigraphy 82.Pulmonary imaging for nonthrombolic disease Part. V Special Oncologic Studies 83.Non PET Oncologic Imaging 84.Lymphoscintigraphy in oncology 85.Positron emission tomography: applications in oncology Part VI. Correlative Imaging 86.Prospective Image Fusion: the role of SPECT/CT and PET/CT 87.Retrospective merging of physiological and anatomical images: software solutions 88.The future of nuclear medicine: molecular imaging and radiotherapy Part VII. Therapy with unsealed sources 89.Therapy of hyperthyroidism 90.The treatment of thyroid malignancies 91.Radionuclide therapy in the peritoneum, pleura, synovium, and hematopoietic system 92.Radionuclide Synovectomy 93.Therapy for painful skeletal metastases 94.Radioimmunotherapy of lymphomas and leukemias 95.Radioimmunotherapy of solid tumors 96.Radioimmunotherapy with alpha-emitting radionuclides Part VIII. Diagnosis of inflammatory disease 97.Gallium imaging 98.Indium-111 labelled leukocyte imaging in the diagnosis of infection and inflammatory disease 99.Imaging inflammation and infection TC 99m HMPAO labeled leukocytes 100.Infection imaging using labeled antibodies and newer agents 101.Correlative imaging of abdominal infection Part IX. Pediatrics 102.Radiopharmaceuticals for pediatric imaging 103.Pediatric skeletal scintigraphy Index