First Aid™ Cases for the USMLE Step 1

Tao Le, MD, MHS, is Assistant Clinical Professor of Pediatrics in the Division of Allergy and Immunology at the University of Louisville. He is also affiliated with the Division of Allergy and Immunology at The Johns Hopkins University School of Medicine.

PART I. GENERAL PRINCIPLESBehavioral SciencesCase 1: Alcohol WithdrawalCase 2: Anorexia NervosaCase 3: Benzodiazepine OverdoseCase 4: DeliriumCase 5: Drug IntoxicationCase 6: Infant Development Case 7: Operant ConditioningCase 8: Opioid WithdrawalCase 9: Sleep PhysiologyCase 10: Sleep StagesBiochemistryCase 1: AlkaptonuriaCase 2: Cyanide PoisoningCase 3: Fragile X SyndromeCase 4: Fructose IntoleranceCase 5: HomocystinuriaCase 6: Hurler's SyndromeCase 7: Lesch-Nyhan SyndromeCase 8: McArdle’s DiseaseCase 9: PhenylketonuriaCase 10: Pyruvate Dehydrogenase DeficiencyCase 11 Tay-Sachs DiseaseCase 12 Thiamine DeficiencyCase 13 Von Gierke’s DiseaseMicrobiology & ImmunologyCase 1: Actinomyces vs NocardiaCase 2: AnthraxCase 3: AscariasisCase 4: AspergillosisCase 5: CandidiasisCase 6: Chagas DiseaseCase 7: CholeraCase 8: Congenital SyphilisCase 9: Creutzfeld-Jakob DiseaseCase 10: Cryptococcal MeningitisCase 11: CystericosisCase 12: DiptheriaCase 13: ElephantiasisCase 14: GiardiasisCase 15: Hand, Foot, and Mouth DiseaseCase 16: HookwormCase 17: InfluenzaCase 18: Kaposi’s SarcomaCase 19: Legionella InfectionCase 20: LeprosyCase 21: Listeria MeningitisCase 22: Lyme DiseaseCase 23: MalariaCase 24: MeaslesCase 25: MononucleosisCase 26: MumpsCase 27: Neisseria meningitidis MeningitisCase 28: OnchocerciasisCase 29: OsteomyelitisCase 30: PinwormCase 31: Pneumocystis jiroveci PneumoniaCase 32: Poison IvyCase 33: PolioCase 34: Pseudomonas aeruginosa InfectionCase 35: RabiesCase 36: RingwormCase 37: Rotavirus InfectionCase 38: SchistosomiasisCase 39: ShinglesCase 40: StrongyloidiasisCase 41: Systemic MycosisCase 42: Toxic Shock SyndromeCase 43: ToxoplasmosisCase 44: TuberculosisCase 45: Yellow FeverPharmacologyCase 1: Acetaminophen OverdoseCase 2: Agranulocytosis Secondary to Drug ToxicityCase 3: Benzodiazepine OverdoseCase 4: Beta-Adrenergic Second Messenger SystemsCase 5: Cholinergic DrugsCase 6: Drug DevelopmentCase 7: Drug-Induced LupusCase 8: PharmacodynamicsCase 9: PharmacokineticsPART II: ORGAN SYSTEMSCardiovascular SystemCase 1: Abdominal Aortic AneurysmCase 2: Aortic StenosisCase 3: AtherosclerosisCase 4: Atrial FibrillationCase 5: Atrioventricular BlockCase 6: Coarctation of the AortaCase 7: Congestive Heart FailureCase 8: Coronary Artery DiseaseCase 9: EndocarditisCase 10: HypertensionCase 11: Kawasaki’s DiseaseCase 12: Myocardial InfarctionCase 13: Obstruction of Superior Mesenteric Artery/ Inferior Mesenteric ArteryCase 14: PericarditisCase 15: Polyarteritis NodosaCase 16: Rheumatic Heart DiseaseCase 17: Temporal ArteritisCase 18: Tetralogy of FallotCase 19: Wegener’s GranulomatosisCase 20: Wolf-Parkinson-White SyndromeEndocrine SystemCase 1: 11-ß Hydroxylase DeficiencyCase 2: 21-ß Hydroxylase DeficiencyCase 3: Addison’s DiseaseCase 4: Conn’s SyndromeCase 5: Cushing's SyndromeCase 6: Diabetes MellitusCase 7: GoutCase 8: Graves’ DiseaseCase 9: HyperparathyroidismCase 10: HypothyroidismCase 11: Multiple Endocrine Neoplasia Type IIACase 12: Painless JaundiceCase 13: PheochromocytomaCase 14: PseudohypoparathyroidismCase 15: ThyroidectomyGastrointestinal SystemCase 1: AchalasiaCase 2: Acute PancreatitisCase 3: Alcoholic CirrhosisCase 4: AppendicitisCase 5: Barrett's EsophagusCase 6: CholelithiasisCase 7: Crigler-Najjar SyndromeCase 8: Diverticular DiseaseCase 9: Esophageal Atresia/FistulaCase 10: GastrinomaCase 11: Hepatitis B Virus InfectionCase 12: Hepatitis C Virus InfectionCase 13: HyperbilirubinemiaCase 14: Lower Gastrointestinal BleedingCase 15: PellagraCase 16: Pseudomembranous Colitis/Clostridium difficile InfectionCase 17: Short Bowel Syndrome/MalabsorptionCase 18: Upper Gastrointestinal Tract BleedingCase 19: Vitamin B12 DeficiencyCase 20: Zollinger-Ellison SyndromeHematology and OncologyCase 1: Acute Intermittent PorphyriaCase 2: Acute Myeloid LeukemiaCase 3: Aplastic AnemiaCase 4: Beta-ThalassemiaCase 5: Breast CancerCase 6: Carcinoid SyndromeCase 7: Colorectal CancerCase 8: Disseminated Intravascular CoagulationCase 9: Gastric CancerCase 10: Glioblastoma MultiformeCase 11: Glucose-6-Phosphate Dehydrogenase (G6PD) DeficiencyCase 12: Head and Neck CancerCase 13: HemochromatosisCase 14: Idiopathic Thrombocytic PurpuraCase 15: Lead PoisoningCase 16: Lung Cancer (Pancoast’s Syndrome)Case 17: Macrocytic AnemiaCase 18: Microcytic AnemiaCase 19: Multiple MyelomaCase 20: NeuroblastomCase 21: OligodendrogliomaCase 22: Ovarian Cancer (Sertoli-Leydig Tumor)Case 23: Pancreatic CancerCase 24: PolycythemiaCase 25: RetinoblastomaCase 26: Sickle Cell AnemiaCase 27: Small Cell Carcinoma of the LungCase 28: SpherocytosisCase 29: Splenic InjuryCase 30: Testicular CancerCase 31: von Willebrand's DiseaseMusculoskeletal System and Connective TissueCase 1: CostochondritisCase 2: Gun Shot Wound to Left FlankCase 3: Hip FractureCase 4: Inguinal HerniaCase 5: Knee PainCase 6: Muscular DystrophyCase 7: NeurofibromatosisCase 8: Osteogenesis Imperfecta Case 9: Rotator Cuff TearCase 10: Subclavian Stab WoundNeurology and PsychiatryCase 1: Alzheimer’s DiseaseCase 2: AutismCase 3: Bipolar DisorderCase 4: Brown-Séquard SyndromeCase 5: Central Cord SyndromeCase 6: Corneal Abrasion/Eye InjuryCase 7: Damage to Recurrent Laryngeal NerveCase 8: DepressionCase 9: Femoral NeuropathyCase 10: Generalized Anxiety DisorderCase 11: GlaucomaCase 12: Gullaine-Barré SyndromeCase 13: Horner's SyndromeCase 14: Huntington’s DiseaseCase 15: HydrocephalusCase 16: Macular DegenerationCase 17: Middle Ear Infection/Ear AnatomyCase 18: MigraineCase 19: Multiple SclerosisCase 20: Myasthenia GravisCase 21: Obsessive-Compulsive DisorderCase 22: Obsessive-Compulsive Personality DisorderCase 23: Panic DisorderCase 24: Parkinson’s DiseaseCase 25: SchizophreniaCase 26: Seizures/Status EpilepticusCase 27: Somatoform DisorderCase 28: Spinal Cord CompressionCase 29: Steroid-Induced ManiaCase 39: StrokeCase 31: Subarachnoid HemorrhageCase 32: Subdural HematomaCase 33: SyncopeCase 34: Tardive DyskinesiaCase 35: Transient Ischemic AttackCase 36: Vestibulo-Ocular ReflexesCase 37: Viral MeningitisCase 38: von Hippel-Lindau DiseaseCase 39: Wernicke-Korsakoff SyndromeCase 40: Ulnar Nerve DamageCase 1: Acute Tubular NecrosisCase 2: Adult Polycystic Kidney DiseaseCase 3: Alport’s SyndromeCase 4: Henoch-Schönlein PurpuraCase 5: HypercalcemiaCase 6: HypokalemiaCase 7: Minimal Change DiseaseCase 8: Nephrotic SyndromeCase 9: PyelonephritisCase 10: Renal Artery Stenosis/Hypertension/Renin-Angiotensin-Aldosterone AxisCase 11: Renal CalculiCase 12: Syndrome of Inappropriate Secretion of ADHCase 13: Transplant ImmunologyCase 14: Urinary RefluxReproductive SystemCase 1: Abruptio PlacentaeCase 2: Bacterial VaginosisCase 3: Breast MassCase 4: Ectopic PregnancyCase 5: EndometriosisCase 6: Fitzhugh-Curtis Syndrome Case 7: Gestational DiabetesCase 8: LeiomyomaCase 9: Paget’s Disease of the BreastCase 10: PreeclampsiaCase 11: Turner's SyndromeRespiratory SystemCase 1: AsbestosisCase 2: AsthmaCase 3: Chronic Obstructive Pulmonary DiseaseCase 4: Community-Acquired PneumoniaCase 5: Congenital Cystic Adenomatoid Malformation of the LungCase 6: Cystic FibrosisCase 7: EmphysemaCase 8: Epiglottis due to Haemophilus influenzae InfectionCase 9: Malignant Pleural EffusionCase 10: Mycoplasma PneumoniaCase 11: Pulmonary EmbolismCase 12: Respiratory AcidosisCase 13: SarcoidosisCase 14: Spontaneous PneumothoraxCase 15: Thoracic Outlet Obstruction (Klumpke's Palsy)