Hepatitis Delta Virus

John L. Casey (Herausgeber)

Buch | Hardcover
XII, 228 Seiten
2006 | 2006
Springer Berlin (Verlag)
978-3-540-29801-4 (ISBN)

Lese- und Medienproben

Hepatitis Delta Virus -
160,49 inkl. MwSt

Hepatitis delta virus which causes severe acute and chronic liver disease was discovered following the detection of a novel antigen-antibody system in hepatitis B virus carriers. Currently, HDV is classified as a subviral satellite of hepatitis B virus. However, unlike other satellite viruses, the dependence of HDV on HBV is limited solely to the provision of an envelope of hepatitis B surface antigen for virus assembly. Research into the molecular virology of the HDV life cycle has revealed a fascinating collection of biology. These insights are now beginning to be translated into new potential treatment strategies. There are currently still an estimated 15 million HDV carriers worldwide.

Structure and Replication of Hepatitis Delta Virus RNA.- HDV RNA Replication: Ancient Relic or Primer?.- HDV Ribozymes.- RNA Editing in Hepatitis Delta Virus.- Post-translational Modification of Delta Antigen of Hepatitis D Virus.- The Role of the HBV Envelope Proteins in the HDV Replication Cycle.- Prenylation of HDAg and Antiviral Drug Development.- Hepatitis Delta Virus Genetic Variability: From Genotypes I, II, III to Eight Major Clades?.- Functional and Clinical Significance of Hepatitis D Virus Genotype II Infection.- Immunology of HDV Infection.- The Woodchuck Model of HDV Infection.

Erscheint lt. Verlag 9.5.2006
Reihe/Serie Current Topics in Microbiology and Immunology
Zusatzinfo XII, 228 p. 18 illus., 1 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 475 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte Antibody • Antigen • antigenomic RNA • cytotoxic T-cell • delta protein • Genetics • genetic variability • HBV envelope proteins • Hepatitis • Hepatitis B • hepatitis delta antigen • immunology • Infection • Liver • liver disease • Posttranslational modification • prenylation • Protein • proteins • Ribozyme • RNA • RNA editing • RNA polymerase • RNA replication • Virology • Virus • woodchuck model
ISBN-10 3-540-29801-0 / 3540298010
ISBN-13 978-3-540-29801-4 / 9783540298014
Zustand Neuware
Haben Sie eine Frage zum Produkt?
Mehr entdecken
aus dem Bereich
und Erste Hilfe an Bord

von Jürgen Graf; Jochen Hinkelbein

Buch | Softcover (2024)
MWV Medizinisch Wissenschaftliche Verlagsgesellschaft
39,95