Lymphoma

B Cell Differentiation and the Origin and Pathogenesis of Human B Cell Lymphomas.- Flow Cytometry for Non-Hodgkin and Hodgkin Lymphomas.- Laser-Based Microdissection of Single Cells from Tissue Sections and PCR Analysis of Rearranged Immunoglobulin Genes from Isolated Normal and Malignant Human B Cells.- PCR GeneScan Analysis of Rearranged Immunoglobulin or T-Cell Receptor Genes for Clonality Diagnostics in Suspect Lymphoproliferations.- Expression Cloning of Antibodies from Single Human B Cells.- Stereotyped B Cell Receptor Immunoglobulins in B Cell Lymphomas.- Flow Cytometric MRD Detection in Selected Mature B-Cell Malignancies.- MRD Detection in B-Cell Non-Hodgkin Lymphomas Using Ig Gene Rearrangements and Chromosomal Translocations as Targets for Real-Time Quantitative PCR and ddPCR.- FISH and FICTION in Lymphoma Research.- Genotype from Phenotype: Using CRISPR Screens to Dissect Lymphoma Biology.- Lymphoma and Leukemia Cell Vulnerabilities and Resistance Identified by Compound Library Screens.- Use of Proximity Ligation Assay to Study Lymphoid Malignancies.- Phosphoproteomic Analysis of Signaling Pathways in Lymphomas.- Single Cell VDJ Sequencing of Normal and Malignant B and T Cells.- Single-Cell Transcriptomic Analysis of Normal and Malignant B Cells.- Multiplexed Immunophenotyping of Lymphoma Tissue Samples.- Genetic Manipulation and Extended Culture of Human Germinal Center B Cells to Model Lymphomagenesis.- Genetic Mouse Models of Lymphomas.- Establishing Patient-Derived Xenograft (PDX) Models of Lymphomas.- Detection and Characterization of Clonal Hematopoiesis.- Detection of Circulating Tumor DNA in Lymphoma Patients.