Bipolar Psychopharmacotherapy

Hagop Akiskal, Distinguished Professor of Psychiatry, Director of International Mood Center, University of California at San Diego, La Jolla, California, USA. Professor Akiskal was awarded the Jean Delay prize by the World Psychiatric Association in 2002 for research work that better bridges the gap between biological, psychological and social aspects of psychiatry and mental health. He has received the Gold Medal for Pioneer Research (Society of Biological Psychiatry), the German Anna Monika Prize for Depression, the NARSAD Prize for Affective Disorders, the French Jules Baillarger and the Italian Aretaeus Prizes for his research on the bipolar spectrum. He is Editor-in-Chief of the Journal of Affective Disorders. Mauricio Tohen, Professor and Head of the Division of Mood and Anxiety Disorders, Department of Psychiatry, University of Texas Health Science Centre, San Antonio, Texas, USA. Professor Tohen is President of The International Society for Bipolar Disorders, 2010 - 2012. Dr. Tohen obtained his MD degree from the National University of Mexico. He completed a residency in Psychiatry at the University of Toronto and a Fellowship in Psychopharmacology at McLean Hospital, Harvard Medical School. He obtained his doctorate in Epidemiology from the Harvard School of Public Health and an MBA from the University of Indiana. From 1988 to 1997 he was the clinical Director of the Bipolar and Psychotic Disorders Program at McLean Hospital. From 1997 to 2008 he worked at Lilly Research Laboratories in Indianapolis, Indiana where he reached the most senior scientific rank of Distinguished Lilly Scholar. In 2009 he was appointed to the Krus endowed chair in Psychiatry at the University of Texas Health Science Centre at San Antonio. His research has focused on the clinical epidemiology and psychopharmacological treatments of bipolar disorder. Professor Tohen has over 200 original publications and over 500 book chapters and scientific abstracts. He has co-edited Mood Disorders Across the Lifespan and Textbook of Psychiatric Epidemiology, and has also edited Comorbidity in Affective Disorders.

List of Contributors. Preface. Chapter 1: The Scope of Bipolar Disorders (Hagop S. Akiskal). Chapter 2: Lithium Treatment: Focus on Long-Term Prophylaxis (Mogens Schou and Paul Grof). Chapter 3: Valproate: Clinical Pharmacological Profile (Charles L. Bowden and Vivek Singh). Chapter 4: Pharmacological Profile and Clinical Utility of Lamotrigine in Bipolar Disorders (David J. Muzina, Joseph R. Calabrese). Chapter 5: Carbamazepine, Other Anticonvulsants and Augmenting Agents (Heinz Grunze). Chapter 6: Olanzapine in Treatment for Bipolar Disorder (Mauricio Tohen, Giedra Campbell, and Daniel Lin). Chapter 7: Haloperidol and Risperidone in Mania (John Cookson). Chapter 8: A Comparison of "Second Generation Antipsychotics" in the Treatment for Bipolar Disorder: Focus on Clozapine, Quetiapine, Ziprasidone and Aripiprazole (Paul E. Keck, Jr. and Susan L. McElroy). Chapter 9: Complex Combination Therapy: The Evolution Toward Rational Polypharmacy in Lithium-Resistant Bipolar Illness (Robert M. Post, Andrew M. Speer and Gabriele S. Leverich). Chapter 10: The Primacy of Mania (Athanasios Koukopoulos). Chapter 11: Diagnostic and Clinical Management Approaches to Bipolar Depression, Bipolar II and Their Comorbidities (Giulio Perugi, S. Nassir Ghaemi and Hagop S. Akiskal). Chapter 12: Bipolarity in Women: Therapeutic Issues (Susan L. McElroy, Lesley M. Arnold and Lori L. Altshuler). Chapter 13: Pediatric Bipolar Disorder: The Promise of Psychopharmacotherapy (Joseph Biederman). Chapter 14: Treatment for Bipolar Disorder in Older Adults (Kenneth I. Shulman). Chapter 15 Psychosocial Interventions in Bipolar Disorders: Rationale and Effectiveness (David J. Miklowitz). Chapter 16: The Pivotal Role of Psychoeducation in the Long-Term Treatment of Bipolar Disorder (Francesc Colom and Eduard Vieta). Chapter 17: The Role of Treatment Setting in the Pharmacotherapy of Bipolar Disorder (Jean-Michel Azorin). Chapter 18: Suicide Prevention (Zoltan Rihmer Chapter 19: Principles of Caring for Bipolar Patients (Hagop S. Akiskal and Kareen K. Akiskal). Index.