Sepsis and Organ Dysfunction

Epidemiology and Clinical Course of Sepsis and MODS.- Epidemiology and Clinical Course of Sepsis.- The Complexities of Sepsis and Organ Dysfunction.- Scoring Systems.- An Overview to Introduce Prognostic Indexes in MODS.- Multiple Organ Dysfunction (MOD) Score.- The Logistic Organ Dysfunction (LOD) System.- Will the Use of Scores Benefit the Individual Patient and Improve Therapy?.- Mediators and Prostaglandins.- Old and New Mediators in Sepsis. The Enigma Is Not Yet Resolved.- Modulating Prostaglandin Metabolism in Sepsis.- DO2/VO2 In Sepsis.- Oxygen Delivery and Consumption Relationships in Sepsis The Role of Inotropic and Vasoactive Drugs.- Coagulation.- Disturbances and Modulators of Coagulation and Fibrinolysis in Sepsis.- Experimental and Clinical Approach.- Therapies Directed against TNF-? and IL-1 during Sepsis.- Effects of Adrenergic Agents on the Hepato-Splanchnic Circulation: An Update.- When to Operate or to Stop Operating and to Plan a Reoperation.- Multiple Therapeutic Agents—Are We Making Progress?.- Neuromuscular Dysfunction.- SIRS and Sepsis-Induced Neuromuscular Dysfunctions.- Prevention and Management of Sepsis and MODS.- Lights and Shadows in Sepsis and Multiple Organ Dysfunction Syndrome (MODS).