mRNA Therapeutics

Foundations, Innovations, and Clinical Applications

Anya Hillery (Autor)

Buch | Softcover

210 Seiten

2024
Academic Press Inc (Verlag)
978-0-443-28934-7 (ISBN)

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mRNA Therapeutics: Foundations, Innovations, and Clinical Applications summarizes the scientific development of mRNA vaccines that have revolutionized the way we treat disease. This approach has the potential to treat a wide range of diseases, including COVID-19, cancer, and infectious diseases. The first section of the book introduces mRNA vaccines, including their history, mechanism of action, and potential applications. The second section delves into the science of mRNA vaccines, covering topics such as the structure of mRNA, the delivery of mRNA to cells, and the immune response to mRNA vaccines.

The third section discusses the future of mRNA technology, exploring potential applications such as cancer therapy, prevention of infectious diseases, and replacement of missing or damaged proteins. This is a valuable resource for scientists, researchers, and clinicians who are interested in the latest developments in mRNA technology. It is also a useful reference for students and professionals who are working in the fields of biotechnology, pharmaceutical science, and vaccine development.

Dr. Hillery’s Ph.D. and post-doctoral research work were in the field of vaccines and nanoparticles (the delivery system for mRNA vaccines) at the Centre for Drug Delivery Research, University College London School of Pharmacy, Brunswick Square, London, UK. As a Senior Lecturer in the University of Brighton, UK, she ran her own research laboratory carrying out extensive research in the fields of nanoparticulate delivery systems and oral vaccines. She has published widely in peer-reviewed scientific journals in the field, presented at numerous international conferences, edited two acclaimed books on drug delivery, been awarded various research grants and received various awards. Dr. Hillery is currently a lecturer in Health Sciences at Saint Louis University (SLU), Madrid Campus, Spain.

Section 1. Foundational Knowledge
1. Introduction to mRNA and mRNA-Based Therapeutics
2. Overview of the Immune System and Introduction to Vaccines.

Section 2. The Science and Delivery of mRNA
3. mRNA Structure, Design Innovations, and Synthesis via IVT
4. Delivery Systems for mRNA

Section 3. Clinical Applications of mRNA
5. mRNA vaccines for COVID-19
6. mRNA-based Cancer Therapeutics
7. Further Therapeutic Applications of mRNA and saRNA

Section 4. mRNA Vaccine Dynamics: Efficacy, Safety and Society
8. Vaccine Efficacy, Safety, and Regulatory Controls
9. Navigating Societal Complexities of mRNA Vaccines

Erscheint lt. Verlag	1.9.2024
Verlagsort	San Diego
Sprache	englisch
Maße	191 x 235 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
ISBN-10	0-443-28934-4 / 0443289344
ISBN-13	978-0-443-28934-7 / 9780443289347
Zustand	Neuware