Recent Advances in Neuropharmacology

Synthesis and inactivation of neurotransmitters.- The effects of electroconvulsive shock on catecholamine function in the locus ceruleus and hippocampus.- Molecular aspects of the neuronal noradrenaline transporter.- Energy requirements for the basal efflux of noradrenaline and its metabolites from adrenergic varicosities.- The effects of type 1 diabetes mellitus and of tobacco smoke on dissipation of catecholamines in pulmonary endothelial cells - a non-neuronal site of uptake1.- Distribution of extraneuronal uptake1 in reproductive tissues: studies on cells in culture.- Extraneuronal inactivation of noradrenaline in tissue culture.- The influence of the estrous cycle on the accumulation of 3H-noradrenaline in rat uterus and on efflux of radioactivity from the uterus.- PC12 cells as a window for the differentiation of neural crest into adrenergic nerve ending and adrenal medulla.- Clinical aspects on presynaptic noradrenaline metabolism.- Effects of imipramine and some tryptamine derivatives on the efflux of 3H-5-hydroxytryptamine from rabbit platelets.- Influence of antidepressant drugs on seizure susceptibility and the anticonvulsant activity of valproate in mice.- Neurotransmitter release and co-transmission.- Noradrenaline-ATP corelease and cotransmission following activation of nicotine receptors at postganglionic sympathetic axons.- Preliminary evidence for noradrenaline and ATP as neurotransmitters in the porcine isolated palmar common digital artery.- Involvement of catecholaminergic neurones of the nucleus of the solitary tract (NTS) in blood pressure regulation.- Vasodilatation by endothelium-derived nitric oxide as a major determinant of noradrenaline release.- Stimulation of noradrenaline release in the cerebral cortex via presynaptic N-methyl-D-aspartate(NMDA) receptors and their pharmacological characterization.- Presynaptic modulation of neurotransmitter release by endogenous angiotensin II in brown adipose tissue.- Selective destruction of preganglionic sympathetic nerves by antibodies to acetylcholinesterase.- Receptors and post-receptor events.- Adenosine receptors in the central nervous system.- Mediation by adenosine of the trophic effects exerted by the sympathetic innervation of blood vessels.- Alpha1- and alpha2-adrenoceptors at different levels of the canine saphenous vein.- Pre- and postsynaptic alpha2 adrenoceptors as target for drug discovery.- Cyclic AMP and adaptive supersensitivity in guinea pig atria.- Molecular aspects of the receptor activation by imidazolines: an overview.- 5-HT4-like receptors in mammalian atria.- Glutamate receptor antagonism: neurotoxicity, anti-akinetic effects and psychosis.- Stereotypy and asymmetry in mice.