Radiation Oncology: Radiobiological and Physiological Perspectives

I.1 The Overall Radiobiological Effect: the Evolution of Radiation Damage.- II.1 Dose Survival Relationships: Methodology, Forms, and Interpretations.- II.2 Some Modifiers of Dose-response Relationships.- II.3 Interaction of Radiation and Chemotherapeutic Agents.- III.1 Radiation Effects on Normal Tissues: General Principles.- III.2 Dose-time-volume Relationships in Normal Tissue Response to Irradiation.- III.3 Early Reacting Tissues: Skin.- III.4 Early Reacting Tissues: the Haematopoietic Tissue.- III.5 Early Reacting Tissues: the Lymphoid Tissue and the Immune Systems.- III.6 Early Reacting Tissues: the Digestive Tract.- III.7 Early Reacting Tissues: the Testes.- III.8 Radiation Effects on the Ovary: a Nonrenewal System.- III.9 Late Reacting Tissues: Radiation-induced Lung Damage.- III.10 Late Reacting Tissues: the Urinary Tract.- III.11 Late Reacting Normal Tissues: Radiation-induced Liver Damage.- III.12 Late Reacting Tissues: Radiation-induced Damage to the Central Nervous System.- III.13 Late Reacting Tissues: Radiation-induced Heart Disease.- IV.1 Tumour Growth: Organization of Tumour Proliferative Activity.- IV.2 Tumour Growth: Patterns, Parameters and Measurement.- IV.3 Analysis of the Growth Parameters of Human Tumours: Clinical Implications.- IV.4 Tumour Radiation Response: A. Response to a Single Dose.- IV.5 Tumour Radiation Response: B. Response to Multifraction and Protracted Low Dose Rate Irradiation.- IV.6 Hypoxia in Solid Tumours and Normal Tissues: Clinical Implications.- IV.7 Estimates of the Outcome of Radiotherapy. Accuracy requirements.