Principles of Antineoplastic Drug Development and Pharmacology

Principles of Drug Development

Cancer Drug Screening, Michael R. Grever
The Human Tumor-Cloning Assay, Axel-R. Hanauske, Susan G. Hilsenbeck, and Daniel D. Von Hoff
Phase I Clinical Trial Design, Rosemarie Mick
The New Drug Approval Process: Clinical and Regulatory Aspects, Renzo Canetta
Development of Biological Agents, Rosemary Mazanet, Mary Ann Foote, and George Morstyn

Principles of Antineoplastic Pharmacology

Clinical Pharmacology of Anticancer Drugs, B. W. Berry and Charles Erlichman
Principles of Pharmokinetics and Pharmacodynamics, Mark J. Ratain and Rosemary Mick
Biochemical Modulation of Cancer Chemotherapy, George A. Sotos and Carmen J. Allegra
Drug Interactions in Cancer Chemotherapy, Francois Lokiec
Drug-Radiation Interactions, Everett E. Vokes
Principles of Chemotherapy Interaction with Biological Agents, Mario Sznol, Christine L. Carter and Dan L. Longo
Hematopoietic Growth Factors and Cancer Chemotherapy, Michael S. Gordon
Dose Intensity, William M. Hryniuk

Principles of Chemotherapy Dosing

Polymorphic Drug-Metabolizing Enzymes, Zhihong Lu and Robert B. Diasio
Human Cytochrome P-450, Frank J. Gonzalez
Cellular Pharmacodynamics of Anticancer Drugs, Peter J. O'Dwyer, Thomas C. Hamilton, Kang-Shen Yao, Robert F. Ozols, and James M. Gallo
Cancer Chemotherapy in the Elderly, Maurice Schneider
Cancer Chemotherapy and Pharmacology in Children, Steven Weitman and Barton A. Kamen
Adaptive Control of Drug Dosage Regimens: Basic Concepts, Relevant Issues, and Clinical Applications, Roger W. Jelliffe
Individualized Dosing of Anticancer Drugs, Alan V. Boddy and A. Hilary Calvert

Principles of Drug Resistance

Multidrug Resistance, Ahmad R. Safa
DNA Topoisomerases and Tumor Cell Resistance to Their Inhibitors, William T. Beck
The Glutathione System and Drug Resistance, Gerald Batist, Robyn L. Schecter, and Moulay A. Alaoui-Jamali
Importance of DNA Repair in Cancer Chemotherapy, M. Eileen Dolan
Resistance to Antimetabolites, Godefridus J. Peters and Gerrit Jansen

Principles of Drug Delivery

Targeted Drug Delivery, Pramod K. Gupta, John B. Cannon, and Anil Kumar Tibrewal
Intra-Arterial Chemotherapy, William D. Ensminger
Intraperitoneal Chemotherapy, Maurie Markman
Intrathecal Chemotherapy, Susan M. Blaney and David G. Poplack
Systemic Infusional Chemotherapy, Jacob J. Lokich and Norwood Anderson
Circadian Pharmacodynamics, William J. M. Hrushesky, Robert de W. Marsh, and Patricia A. Wood