Acne and Its Therapy

Guy F. Webster, Anthony V. Rawlings

Overview of the Pathogenesis of Acne. Cell Biology of the Pilosebaceous Unit. Sebum Secretion and Acne. Molecular Biology of Retinoids and Their Receptors. Molecular Biology of Peroxisome Proliferator Activated Receptors in Relation to Sebaceous Glands and Acne. Antimicrobial Peptides and Acne. Hormonal Influences in Acne. Antimicrobial Therapy in Acne. Topical Retinoids. Phototherapy and Laser Therapy of Acne. Benzoyl Peroxide and Salicylic Acid Therapy. Treating Acne with Octadecenedioic Acid. The Effect of Sphingolipids as a New Therapeutic Option for Acne Treatment. 5-alpha Reductase and Its Inhibitors. Sebum: Physical-Chemical Properties, Macromolecular Structure, and Effects of Ingredients. Targeted Delivery of Actives from Topical Treatment Products to the Pilosebaceous Unit. Topical Theraoy and Formulation Principles. In Vitro Models for the Evaluation of Anti-acne Technologies.