Viral Hepatitis

Professor Howard Thomas, Department of Medicine, St Mary's Hospital Medical School, London Professor Arie Zuckerman, The Dean's Office, Royal Free School of Medicine, London Professor Stanley Lemon, Dean of Medicine, Departments of Microbiology & Immunology and Internal Medicine, University of Texas Medical Branch, Texas

Preface.Contributors.Section 1.1. Liver stem cells in persistent viral infection, liver regeneration and Cancer.2. The role of the liver in the immune response.Section II - .3. Clinical Features of Hepatitis.4. Diagnosis.5. Evolution of hepatitis viruses.Section III - Hepatitis A Virus .6. Structure and Molecular Virology.7. Epidemiology.8. Natural History and Experimental Models..9. Prevention.Section IV - Hepadnaviridae .10. Structure and Molecular Virology.11. Epidemiology of Hepatitis B..12. Avihepadnaviridae..13. Woodchuck Hepadnaviruses..14. Molecular Variants of Hepatitis B Virus - surface antigen.15. Molecular Variants of Hepatitis B Virus - core antigen.16. Natural History of Chronic Hepatitis B and Hepatocellular Carcinoma.17. Hepatocellular Carcinoma: Molecular Aspects in hepatitis B.18. Pathogenesis of Chronic Hepatitis B - animal studies.19. Pathogenesis of Chronic Hepatitis B - human studies.20. Treatment of Chronic Hepatitis B.21. Management of drug resistant variants.22. Liver Transplantation in the Management of Chronic Viral Hepatitis.23. Protection against hepatitis B.SECTION V: Hepatitis C Virus.24. Structure and Molecular Virology..25. Epidemiology.26. Immune response to HCV in acute & chronic infection.27. Chimpanzee model of HCV.28. Autoimmune disorders associated with hepatitis C.29. CNS complication of HCV infection.30. In vitro replication models of HCV..31. Small animal models of Hepatitis C.32. Progression of Hepatitis C.33. Natural History of Chronic Hepatitis C and Hepatocellular Carcinoma.34. Treatment of Chronic Hepatitis C.35. New drugs for management of hepatitis C.36. Prevention of hepatitis C.Section VI - Hepatitis D Virus.37. Structure and Molecular Virology.38. Epidemiology Natural History.39. Treatment of Hepatitis D.Section VII - Hepatitis E Virus.40. Structure and Molecular biology.41. Hepatitis E as a Zoonotic Disease..42. Epidemiology, Natural History and Experimental Models Diagnosis -.43. Prevention.Section VIII - Clinical Aspects of Viral Liver Disease.44. Etiology of Fulminant Hepatitis.45. Treatment of Fulminant Hepatitis.46. Transfusion-Associated Hepatitis.47. Hepatitis and Hemophila.48. Occupational Aspects of Hepatitis.49. Neonatal and Pediatric Infection.50. Management of Hepatocellular Carcinoma.51. Application of Molecular Biology to the Diagnosis of Viral Hepatitis.52. Hepatitis in HIV-infected Persons.53. Treatment of extra-hepatic diseases caused by HBV & HCV.54. The Histologist's Role in Diagnosis and Management of Chronic Hepatitis B & C.55. Disinfection and Sterilization.56. Mechanisms of interferon resistance.57. Novel cytokines for all hepatitis.58. New in vitro testing systems.59. New vaccine technology (oral vaccines/adjuvants).60. Safety of hepatitis vaccines.61. History of hepatitis.Index.