Wall and Melzack's Textbook of Pain

Section 1. Neurobiology of pain 1. Peripheral mechanisms of cutaneous nociception 2. Cellular and molecular properties of primary afferent neurons 3. Inflammatory mediators and modulators of pain 4. Neuroanatomical substrates of spinal nociception 5. Plasticity and pain: role of the dorsal horn 6. Representation of pain in the brain 7. Central nervous system mechanisms of pain modulation 8. Development of pain pathways and mechanisms 9. The genetics of pain 10. Animal models of pain 11. Ascending projection systems 12. Autonomic-endocrine-immune interactions in acute and chronic pain 13. Itch Section 2. Assessment and psychology of pain 14. Emotions and psychobiology 15. Cognitive and learning aspects 16. Psychiatric disorders and pain 17. Studies of pain in human subjects 18. Pain assessment in adult patients 19. Measurement and assessment of paediatric pain 20. Assessment of pain beliefs, coping, and function 21. Hypnotic analgesia 22. The cognitive-behavioural approach to pain management 23. Pain, opiates and addiction 24. Placebo analgesia Section 3. Pharmacology and Treatment of Pain 25. Central pharmacology of nociceptive transmission 26. Methods of therapeutic trials 27. Opiates: basic mechanisms 28. Opioids: clinical use 29. Antipyretic analgesics: basic aspects 30. NSAIDs and Coxibs: clinical use 31. Antidepressant analgesics: a systematic review and comparative study 32. Anticonvulsant medications in neuropathic pain 33. Local anaesthetic blocks and epidurals 34. Cannabinoids 35. Analgesic drugs in development 36. Supratentorial neurosurgery for the treatment of pain 37. Spinal cord and brain stimulation 38. Transcutaneous electrical nerve stimulation and acupuncture 39. Peripheral and central nervous system surgery for pain 40. Physiotherapy and pain Section 4. Clinical states: Deep somatic tissue 41. Basic mechanisms of deep somatic pain 42. Postoperative pain and its management 43. Osteoarthritis and rheumatoid arthritis 44. Myofascial pain and fibromyalgia syndrome 45. Surgical treatment for back and neck pain 46. Low back pain 47. Repetitive strain injury Section 5. Viscera 48. Visceral pain: basic mechanisms 49. Thorax 50. A clinical perspective on abdominal pain 51. Genitourinary pain 52. Obstetric pain Section 6. Clinical States: Headache and facial pain 53. Acute and chronic dental and orofacial pain 54. Headache 55. Primary neurovasuclar headache 56. Tension-type headache 57. Pain in and around the eye Section 7. Clinical states: Neuropathic pain 58. Response of nerves to injury in relation to neuropathic pain 59. Mechanisms of experimental neuropathic pain: integration from animal models 60. Central consequences of peripheral nerve damage 61. Phantom limb 62. Painful peripheral neuropathies 63. Trigeminal and glossopharyngeal neuralgia 64. Complex regional pain syndromes 65. Root disorders and arachnoiditis 66. Pain following spinal cord injury 67. Central pain 68. Pharmacological therapy for neuropathic pain Section 8. Clinical states: Cancer pain 69. Cancer pain: causes, consequences and therapeutic opportunities 70. The assessment of cancer pain 71. Analgesic therapy and palliative care in children 72. Cancer pain: treatment overview 73. Pain control in the care of the dying Section 9. Clinical States: Special cases 74. Pain in the elderly 75. Sex and gender differences in pain and its relief 76. Epidemiology of pain Index