Morphofunctional and Neurochemical Aspects of the Mammalian Carotid Body - Nikolai E. Lazarov, Dimitrinka Y. Atanasova

Morphofunctional and Neurochemical Aspects of the Mammalian Carotid Body

Buch | Softcover
XIV, 165 Seiten
2023 | 1st ed. 2023
Springer International Publishing (Verlag)
978-3-031-44756-3 (ISBN)
96,29 inkl. MwSt

This new volume of the book series Advances in Anatomy, Embryology and Cell Biology provides a complete and exhaustive overview of the morphofunctional organization of the mammalian carotid body, a polymodal chemosensory organ responsible for the maintenance of blood gas homeostasis.

The authors review the state of the art of the neurochemical anatomy of carotid body´s cell populations with a special reference to their structural and neurochemical plasticity. The essential role of this organ in the generation, progression and maintenance of cardiorespiratory and metabolic diseases in humans and other mammals is presented. Finally, the book summarizes current knowledge on the stem cell niche in the mammalian carotid body and discusses its contribution to replacement cell therapy and other potential applications in translational research.  

This book represents an essential reading for physiologists, anatomists, cell, and developmental biologists, as wellas physicians, veterinarians, and biomedical researchers.


lt;b>Dr. Nikolai E. Lazarov received his MD from the Medical University of Sofia in 1981, his PhD in Neurobiology in 1991, and his DSc in 2000. Dr. Lazarov became Associate Professor in 1994 and was promoted to a Full Professor in 2001. Currently he is a Professor of Anatomy and Cell Neurobiology at the Department of Anatomy and Histology to the Medical University of Sofia and Head of the same department. He is also a collaborating Professor and Head of the Department of Synaptic Signaling and Communications to the Institute of Neurobiology of the Bulgarian Academy of Sciences. Dr. Lazarov was an AvH Fellow in Ulm and Munich, Germany. He has been a Visiting Professor at the universities of Antwerp, Belgium, Leiden, the Netherlands, Ulm and Munich, Germany, and Bern, Switzerland. His research interests are in the areas of neuroscience, with a focus on functional morphology and neurochemistry of the trigeminal sensory system, and also on peripheral arterial chemoreceptors. He has ^2000 times. He has an h-index = 22 (Scopus). Dr. Lazarov is the current President of the Bulgarian Anatomical Society. He was Chairman of the Executive Board of the Bulgarian National Science Fund and later its Vice President.


Dr. Dimitrinka Y. Atanasova is a research Associate Professor at the Department of Synaptic Signaling and Communications at the Institute of Neurobiology to the Bulgarian Academy of Sciences. She received a master's degree in Biology at Sofia University "St. Kliment Ohridski" in 2000 and a PhD degree in Morphology at the Institute of Experimental Morphology, Pathology and Anthropology with a Museum, Bulgarian Academy of Sciences in 2015. Her scientific interests are in the field of experimental morphology and, in particular, the carotid body morphology and neurochemistry. According to the data in Scopus she has 47 publications and H index = 12.

1 Carotid Body: The Primary Peripheral Arterial Chemoreceptor.- 2 History and Recent Progress in Carotid Body Studies.- 3 General Morphology of the Mammalian Carotid Body.- 4 Structural Plasticity of Carotid Bodies.- 5 Mechanisms of Chemosensory Transduction at the Carotid Body.- 6 Neurochemical Anatomy of the Mammalian Carotid Body.- 7 Neurochemical Plasticity of Carotid Bodies.- 8 Carotid Body Dysfunction and Mechanisms of Disease.- 9 Stem Cell Niche in the Mammalian Carotid Body.- 10 Carotid Body and Cell Therapy.- 11 The Carotid Body: a Tiny Structure with Many Roles.

Erscheinungsdatum
Reihe/Serie Advances in Anatomy, Embryology and Cell Biology
Zusatzinfo XIV, 165 p. 47 illus., 42 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Gewicht 347 g
Themenwelt Studium 1. Studienabschnitt (Vorklinik) Anatomie / Neuroanatomie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Schlagworte Carotid Body • chemoreception • dopamine • gasotransmitters • glomus cells • Histamine • Hypertension • Hypoxia • neurochemical plasticity • Neuropeptides • Neurotrophic Factors • Oxygen sensing • petrosal ganglion • Spontaneously hypertensive rat • Stem cell niche • structural plasticity • superior cervical ganglion • sustentacular cells • sympathetically-mediated diseases
ISBN-10 3-031-44756-5 / 3031447565
ISBN-13 978-3-031-44756-3 / 9783031447563
Zustand Neuware
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