Gene Therapy of Cancer
Springer-Verlag New York Inc.
978-1-0716-2443-2 (ISBN)
Authoritative and cutting-edge, Gene Therapy of Cancer: Methods and Protocols, Third Edition aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
1. Brief Introduction to Current Cancer Gene Therapy
Dennis Kobelt, Jessica Pahle, and Wolfgang Walther
Part I: Strategies in Cancer Gene Therapy
2. Minicircles for CAR T Cell Production by Sleeping Beauty Transposition - A Technological Overview
Sabrina Prommersberger, Razieh Monjezi, Ram Shankar, Marco Schmeer, Michael Hudecek, Zoltán Ivics, and Martin Schleef
3. Generation of CAR-T Cells with Sleeping Beauty Transposon Gene Transfer
Sabrina Prommersberger, Razieh Monjezi, Lacramioara Botezatu, Csaba Miskey, Maximilian Amberger, Katrin Mestermann, Michael Hudecek, and Zoltán Ivics
4. Generation of Redirected Engineered Human Chimeric Antigen Receptor (CAR) T cells
Mario Bunse and Uta E. Höpken
5. TCR- and CAR-engineering of Primary Human T cellsInan Edes, Julian Clauss, Rainer Stahn, Alberto Sada Japp, and Felix K. M. Lorenz
6. TCR Gene Therapy for Cancer
Simone Rhein and Nese Çakmak-Görür
7. Gene Gun Her2/neu DNA Vaccination: Evaluation of Vaccine Efficacy in a Syngeneic Her2/neu Mouse Tumor Model
T. Nguyen-Hoai, O. Hohn, A. Pezzutto,and J. Westermann
Part II: Suicide Gene Therapy
8. Construction of Minicircle Suicide Genes Coding for Ribosome-Inactivating Proteins
Alexander Sonntag, Hardy Mitdank, and Alexander Weng
9. Claudin-targeted Suicide Gene Therapy for Claudin-Overexpressing Tumor Cells by Using Modified Clostridium Perfringens Enterotoxin (CPE)
Laura-Sophie Beier, Jörg Piontek, Anna Piontek, Jonas Protze, Dennis Kobelt, and Wolfgang Walther
Part III: Gene Suppression and Signaling Modulation Therapy for Cancer
10. Bioengineered RNA Therapy in Patient-Derived Organoids and Xenograft Mouse Models
Mei-Juan Tu, Colleen M. Yi, Gavin M. Traber, and Ai-Ming Yu
11. Application of Transcription Factor Decoy Oligodeoxynucleotides (ODNs) for Cancer Therapy
Behrooz Johari and Mohammad Moradi
Part IV: Oncolytic Therapy for Cancer
12. NK Cell Effector Functions and Bystander Tumor Cell Killing in Immunovirotherapy Alessia Floerchinger and Christine E. Engeland
13. A qPCR-based Method for Quantification of Replication Competent Adenovirus (RCA) in Conditionally Replicating Oncolytic Adenoviruses
Erik Yngve, Menghan Gao, and Di Yu
14. Generation of a microRNA-regulated oncolytic Coxsackievirus B3
Babette Dieringer, Leslie Elsner, Ahmet Hazini, Jens Kurreck, and Henry Fechner
15. Visualized Cancer Immunotherapy with Engineered Salmonella typhimurium
Yujie Sun and Jin Hai Zheng
Part V: Translational Aspects for Cancer Gene Therapy
16. Cancer Gene Therapy: Development and Production of Lentiviral Vectors For Gene Therapy
Ana S. Coroadinha
17. Capillary Gel Electrophoresis (CGE) for Quality Control of Plasmid DNA in Gene Therapy: quality control of 20-years stored GMP-grade Plasmid DNA
Schmeer M, Schleef M, Shankar R, Kobelt D, and Walther W
18. Efficient Generation of Superior Dumbbell-Shaped Non-viral DNA Delivery Vectors Using 1-2-3 Gap-primer PCR
Pei She Loh and Volker Patzel
| Erscheinungsdatum | 28.06.2023 |
|---|---|
| Reihe/Serie | Methods in Molecular Biology |
| Zusatzinfo | 47 Illustrations, color; 18 Illustrations, black and white; XI, 342 p. 65 illus., 47 illus. in color. |
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 178 x 254 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie |
| Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
| Schlagworte | CAR-T cells • Gene replacement • Gene suppression • Oncolytic therapy • suicide gene therapy |
| ISBN-10 | 1-0716-2443-1 / 1071624431 |
| ISBN-13 | 978-1-0716-2443-2 / 9781071624432 |
| Zustand | Neuware |
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