Reperfusion Therapy for Acute Myocardial Infarction

ERIC R. BATES is Professor of Internal Medicine at the University of Michigan. Dr. Bates received his M.D. from the University of Michigan Medical School, Ann Arbor, and trained in internal medicine and cardiology at the University of Michigan Hospitals. His major clinical interests include acute myocardial infarction, acute coronary syndromes, and coronary artery disease. His research efforts have focused on fibrinolytic and catheter-based reperfusion therapy for acute myocardial infarction and cardiogenic shock, antiplatelet and anticoagulant therapy for coronary thrombosis, and coronary artery revascularization. Dr. Bates has served on the steering committees for several important international multicenter randomized clinical trials. He serves on the editorial boards of the American Journal of Cardiology, the European Journal of Cardiology, the Journal of the American College of Cardiology, the American Heart Journal, Catheterization and Cardiovascular Interventions, and Cardiology News. Dr. Bates is a member of the ACC/AHA writing committee to update the 1999 guidelines for acute myocardial infarction. He is also a member of the American Board of Internal Medicine Interventional Cardiology Test Committee.

Background. Chapter 1. Historical Milestones. Chapter 2. Pathophysiology of Myocardial Infarction. Chapter 3. Successful Myocardial Reperfusion. Fibrinolytic Reperfusion. Chapter 4. Infusion Fibrinolytic Therapy. Chapter 5. Bolus Fibrinolytic Therapy. Chapter 6. Treatment Opportunities with Fibrinolytic Therapy. Catheter-based Reperfusion. Chapter 7. Primary PCI. Chapter 8. Rescue PCI. Chapter 9. Facilitated PCI. Chapter 10. Primary PCI without On-site Surgery. Chapter 11. Transfer for Primary PCI. Adjunctive Therapy. Chapter 12. Antiplatelet Agents. Chapter 13. Anticoagulant Agents. Chapter 14. Myocyte Protection by Pharmacological Therapy. Chapter 15. Myocyte Protection by Device Therapy. Challenges and Opportunities. Chapter 16. Optimal Strategies for Emergency Medical System and Emergency Department Triage. Chapter 17. Management of Complications. Chapter 18. Myocyte Regeneration. Chapter 19. The Future of Reperfusion Therapy. Appendix. ACC/AHA and ESC Guidelines.