Retinal Degenerative Diseases XIX

High Resolution Imaging Mass Spectrometry of Human Donor Eye: Photoreceptor Cells and Basal Laminar Deposits of Age-related Macular Degeneration.- The non-canonical role of Complement Factor H in Retinal Pigment Epithelium (RPE) cells and implications for Age-related Macular Degeneration.- Macular Pigment Carotenoids and Bisretinoid A2E.- Disturbed matrix metalloproteinases activity in age-related macular degeneraton.- Current views on Chr10q26 contribuiton to age-related macular degeneration.- Untargeted lipidomic profiling of aged human retina with and without age-related macular degeneration (AMD).- Decoding Race and Age-Relation Macular Degeneration: GPR 143 Activity is the Key.- Peroxisome proliferator-activated receptor gamma coactivator 1 alpha ( PGC-1x): a transcriptional regulator at the interface of aging and age-related macular degeneration?.- Regulation of ABCA1 by miR-33 and miR-34a in the aging eye.- The role of gene expressionregulation on genetic risk of Age-related Macular Degeneration.- Elastin layer in Bruch's membrane as a target for immunizatio or tolerization to modulate patthology in the mouse model of somke-induced ocular injury.- Repuprosing drugs for treatment of age-relation macular degeneration.- Extracellular Vesicle RNA Contents as Biomarkers for Ocular Diseases.- Proteomics of retinal extracellular vesicles: a reviw inot an unexplored mechanism in retinal health and AMD pathogenesis.- Prime Editing Strategy to Instally the PRHP2 c.828+1G A mutations.- Analysis of CRB1 Pathogenic Variants Correctable with CRISPR Base and Prime Editing.- Generation of an Avian Myeloblastosis Virus (AMV) Reverse Transcriptase Prime Editor.- Pre-existing neutralizing antibodies against different adeno-associated virus serotypes in humans and large animal models for gene therapy.- Optimization of Capillary-based Western Blotting for MYO7A.- AAV Serotypes and Their Suitability for RetinalGene Therapy.- Gene Augmentation ofautosomal dominant CRX-associated retinopathies.- Txnip gene therapy of retinitis pigmentosa improves cone health Factors affecting readthrough of natural versus premature termination codons.- Integrating Computational Approaches to Predict the Effect of Genetic Variants on Protein Stability in Retinal Degenerative Disease.- Network biology and medcine to resuce: Applications for retinal disease mechanisms and therapy.- Non-sydromic Retinal Degeneration Caused by Pathogenic Variants in Joubert Syndrome Genes.- Exonic variants that affect splicing- an opportunity for "hidden" mutations causing inherited retinal diseases.- Enhanced S-cone Syndrome, a Mini-Review.- The role of microglia in Inherited Retinal Diseases.- CD68: potential contributor to inflammation and RPE cell dystrophy.- Gene Expression of Clusterin, Tissue Inhibitor of Metalloproteinase-1, and Their receptors in Retinal Pigment Epithelial Cells and Muller Glial Cells is Modulated by Inflammatory Stresses.- Axonal Transport Defects in Retinal Ganglion Cells.- Connexins biology in the pathophysiology of retinal diseases.- Role of Nuclear NAD +in Retinal Homeostasis.- Retinal pigmented epithelium-derived ectopic norrin does not promote intraretinal angiogenesis in transgenic mice.- Caveolin-1 Muller glia exist as heat-resistant,high molecular weight complexes.- Role of VLC-PUFAs in Retinal and Macular Degeneration.- Ocular amyloid , condensates, and aggregates - higher order protein assemblies participate in both retinal degeneration and function.- Photoreceptor ion channels in signaling and disease.- The role of peripherin-2 /ROM1 complexes in photoreceptor outer segment disc morphogenesis.- Human mutations in Arl3, a small GTPase involved inlipidated cargo delibery to the cilia cause retinatl dystropthy.- Genotype-Phenotype Association in ABCA4-Associated Retinopathy.- Retinal pathoconnectomics: A Window into Neurodegeneration.- The role of Ceramide in Inherited Retinal Disease Pathology.- Extracelluar Matix: the Unexplored Aspects of Retinal Pathologies and Regeneration.- Role of TFEB in diseases assocaited with lysosomal dysfunction.- Retinoic acid receptor -related oprhan receptors (RORs) in eye development and disease.- A novel mouse model for Late-Onset Retinal Degeneration (L-ORD) devekios RPE abnormalities due to the loss of C1qtnf5/Ctrp5.- Comparison of mouse models of autosomal dominant retinitis pigmentosa due to P23H muations of Rhodopsin.- Compensatory Cone-Mediated Mechanisms in Inherited Retinal Degeneration Mouse Models: A Functional and Gene Expression Analsyis.- Inhibition of Ryanodine Receptor 1 Reduces Endoplasmic Reticulum (ER) Sress and Promotes ER Protein Degradation in Cyclic Nucleotide-gated Channel Deficiency.- Mouse choroid proteome revisited: foucs on aging.- Morphological and functional comparison of mice models for retinitis pigmentosa.- Current Advancements in Mouse Models of Retinal Disease.- Single-cell ItrnacriptomicProfiling of Muller Glia in the rd10 Retina.- Methods for in vivo characterization of proteostatis in the mouse retina.- Absence or PRCD leads to dysregulation in lipie Homeostatis resulting in disorganizationof photorecptor outer segment structure.- Expansion Microscopy of Mouse Photoreceptro Cilia.- Rod photorecptor specific ablation of Metformin target, AMPK, in preclinical model of autosomal recessvie retinitis pigmentosa.- TLR2 is highly overexpressed in retinal myeloid cells in the rd10 mouse model of retinitis pigmentosa.- Environmental light has an essentail effrect on the diseasae expression in a dominant RPE65 mutation.- Microglia Preserve Visual Function in A Mouse Model of Retinitis Pigmentosa with Rhodopsin-P23H Mutant.- Measuring the release of lactate from wild-type and rd1 mouse retina.- Aerobic glycolysis in photorecptors supports energy demand in the absence of mitochondrial coupling.- Redox Status in Retinitis Pigmentosa.- Perspectives on retinal dolichol metabolismand visual deficits in dolichol metalbolism-associated inherited disorders.- Retinal metabolic profile on IMPG2 deficiency mice with subretinal lesions.- Glutathione-coating of liposomes enhances the delivery of hydrophillic cargo to the inner nuclear layer in retinal cultures.- Modification of Mueller glial cell fate and proliferation with the use of small molecules.- A potential neuroprotective role for pyruvate kinase 2 in retinal degeneration.- Critical role of VEGF as a direct regulator of photorecptor function.- Lysine Ubiquitylation Drives Rhodopsin Protein Turnover.- In-silico prediction of MYO!C Rhodopsin Interactions and its Significance in Protein Localization and Visual Function.- A ciliary branched actin netowrk drives photoreceptor disc morphogenesis.- Revisiting the daily timing of POS phagocytosis.- Inhibition of Bacterial Peoptidoglycan Cytopahty by Retina Pigment Epithelial PGRP2 Amidase.- Understanding ischemic retinopathies: the role of Succinate and its recpto^T mutation.- Inducing neural regeneratio nfrom glia using proneural bHLH transcription factors.