Orthopedic Surgical Oncology For Bone Tumors

Dr. Harzem Özger graduated from the medical school at Istanbul University Istanbul Faculty of Medicine in 1979. He completed his residency training in the Dept. of Orthopaedics and Traumatology of the same institution in 1984 with his thesis on “Resurfacing Arthroplasty in Hip Surgery”, which was based on his studies in Istanbul, Berlin and Heidelberg. In 1989, he gained experience in tumor surgery at the Medical University of Vienna’s Dept. of Orthopaedics, under the supervision of Prof. Rainer Kotz. Upon his return to Istanbul, he established the "Bone and Soft Tissue Tumors" registry at his home clinic. After becoming an Associate Professor in 1990, he worked almost exclusively in the field of orthopedic oncology and received a full professorship in 1996. His clinical practice and research focus on biological reconstruction using vascular fibula and liquid nitrogen recycled autografts, nonbiological reconstruction with tumor prosthesis, spinopelvic tumor surgery, extreme limb salvage in massive or recurrent tumors utilizing radiotherapy, complex foot reconstruction after tumor resection, limb lengthening and deformity correction and wound management in orthopedic oncology. Since his retirement from Istanbul University in 2016, he has continued his private practice and academic work as the head of Istanbul Orthopedic Oncology Group. He is a member of the Turkish Musculoskeletal Tumour Society (TMTS), International Society of Limb Salvage (ISOLS), European Musculoskeletal Oncology Society (EMSOS), Asia Pacific Musculoskeletal Tumour Society, Musculoskeletal Tumor Society (MSTS) and International Skeletal Society (ISS). Dr. Franklin H. Sim graduated from Dalhousie University Medical School in 1964. He completed his orthopedic residency training at Mayo Clinic and was inspired by Dr. Jack Ivins in the area of musculoskeletal oncology.  Dr. Sim became a leading innovator and proponent of limb sparing surgery in patients with bone and soft tissue tumors in the 1970s. He was a founding member of the Musculoskeletal Tumor Society and has been active in the International Society of Limb Salvage (ISOLS) and the International Skeletal Society (ISS). Doctor Sim has been a member of the Mayo Clinic faculty for the past 47 years, and he has trained hundreds of residents and more than 50 orthopedic oncology fellows from the United States and overseas. Dr. Ajay Puri is currently Professor and Head of Surgical Oncology, Chief of Orthopaedic, Oncology and Head of the Tissue Bank at Tata Memorial Centre, Mumbai, India. He served as President of the Asia Pacific Musculoskeletal Tumor Society, Founder President of the Indian Musculoskeletal Oncology Society and as past Chairman of the Indian Orthopaedic Association (Oncology). He is also Professor (courtesy faculty) of Materials Science and Engineering at the Department of Materials Science & Engineering, College of Engineering, University of North Texas, USA. He is actively involved in clinical, biomedical and basic research and is the principal investigator in many studies. He is a member of the Global Steering Committee of the International Sarcoma Kindred Study (ISKS), the largest multi institutional international trial aimed at understanding the genetic background of sarcomas. He has developed a low cost indigenous megaprosthesis for limb salvage after oncologic reconstruction that is now extensively used in the country and other Asian and African nations and has also pioneered and popularised novel methods of biological reconstruction after oncologic resection. He serves on the editorial board of Bone & Joint Journal (formerly JBJS.Br.), Bone & Joint-360, Bone & Joint – Open, Sarcoma and Frontiers in Orthopedic Surgery and has published more than a hundred and fifty papers as well as numerous book chapters. Dr. Levent Eralp attended medical school at Istanbul University Istanbul Faculty of Medicine and graduated in 1991. He completed his residency training in the Dept. of Orthopaedics and Traumatology of the same institution in 1995. He visited Staatskrankenhaus Holzminden, Germany for joint replacement training in 1997, University Hospital Kanazawa, Japan in 2003 orthopedic oncology and external fixation training with SICOT scholarship, Munich, Germany also in 2003 for lengthening with Fitbone training and Resurgens Orthopedics, Atlanta, USA for musculoskeletal infection training in 2004. Dr Eralp gained associate professorship in 2003 and full professorship in 2009 from his home institution. He also holds a master of science degree from University of Istanbul, Institute of Oncology, Epidemiology and Biostatistics since 2001. His professional areas of interest include orthopedic oncology, musculoskeletal infections, external fixation, adult reconstruction, total joint replacement, trauma surgery and complex pediatric reconstructions. He has contributed to numerous internationally published books on limb reconstruction as editor and chapter author. He has authored approximately 150 scientific papers and participated in the organization of numerous courses and conferences both at national and international level.  He holds memberships in International Society of Orthopaedic Surgery and Traumatology (SICOT), International Society of Limb Salvage (ISOLS), Limb Lengthening and Reconstruction Society (LLRS – USA) and American Academy of Orthopedic Surgeons (AAOS). Dr Eralp continues his clinical practice in his private clinic as well as in VKV American Hospital, Istanbul.

Part 1: Philosophy of limb salvage surgery.-1. When and why biological/ implant reconstruction?.- Part 2: Mobile Spine.- 2. Biological reconstruction using frozen autograft in total en bloc spondylectomy for spinal tumors.-3. Implant Reconstruction of the Mobile Spine.- Part 3: Sacrum.- 4. Biological Sacral Reconstruction.- 5. Total Sacrectomy without Spinopelvic Reconstruction.- 6. mplant Reconstruction of the Sacrum: modular sacrum prosthesis.- Part 4: Pelvis.-7.  Biological Reconstruction of the Pelvis - I: liquid nitrogen treated autograft & onlaid free vascular fibula.- 8. Biological Reconstruction of the Pelvis - II: femoral head plus total hip replacement.- 9.      Implant Reconstruction of the Pelvis - I: modular hemipelvic prosthesis.- 10.   Implant Reconstruction of the Pelvis - II: modular pedestal cup prosthesis.-11.   Implant Reconstruction of the Pelvis - III: high acetabular placement & prosthetic femoral extension.-12.   Implant Reconstruction of the Pelvis - IV: 3D-printed custom-made prosthesis.- Part 5: Proximal femur.-13. Biological Reconstruction of the Proximal Femur With extracorporeally irradiated autograft.-14. Implant Reconstruction of the Proximal Femur: Modular Prosthesis.-15.   Prosthetic reconstruction for soft tissue sarcomas with bone involvement.- Part 6: Femoral diaphysis.-16.   Biological Reconstruction of the Femoral Diaphysis: Van Nes rotationplasty.-17.   Implant Reconstruction of the Femoral Diaphysis - I: intercalary femur prosthesis.-18.   Implant Reconstruction of the Femoral Diaphysis - II: short-segment dynamic-compression stem.-19.   Implant Reconstruction of the Femoral Diaphysis - III: percutaneous ossoeintegrated prosthesis.- Part 7: Distal femur.-20.   Biological Reconstruction of the Distal Femur - I: massive allograft & inlaid free vascular fibula.- 21.   Biological Reconstruction of the Distal Femur - II: resurfacing allograft-prosthesis composite.-2 2.   Biological Reconstruction of the Distal Femur - III: liquid nitrogen treated autograft & inlaid free vascular fibula (the "frozen hotdog").- 23.   Implant Reconstruction of the Distal Femur - I: modular prosthesis.- 24.   Implant Reconstruction of the Distal Femur - II: joint-preserving resection & reconstruction with image-guided computer navigation.- 25.   Implant Reconstruction of the Distal Femur - III: expandable prosthesis.-26.   Implant Reconstruction of the Distal Femur - IV: prosthesis revision.- Part 8: Proximal tibia.- 27.   Biological Reconstruction of the Proximal Shaft of Tibia - I: Pedicle frozen autograft.- 28.   Biological Reconstruction of the Proximal Tibia - II: Distraction-Epiphysiolysis before resection of the tumor.- 29.   Implant Reconstruction of the Proximal Tibia: modular prosthesis   rotational gastrocnemius flap.-Part 9: Tibial diaphysis and ankle.- 30.   Biological Reconstruction of the Tibial Diaphysis & Ankle - I: Ilizarov technique.- 31.   Biological Reconstruction of the Tibial Diaphysis & Ankle - II: fibular centralization technique.-32.   Biological Reconstruction of the Tibial Diaphysis & Ankle - III: arthrodesis with massive allograft.-33.   Implant Reconstruction of the Tibial Diaphysis & Ankle: 3D-printed custom-made prosthesis .- Part 10: Foot.- 34.   Biological Reconstruction of the Foot free vascular iliac flap.- 35.   Implant Reconstruction of the Foot 3D-printed custom-made prosthesis.- Part 11: Shoulder girdle.- 36.   Biological Reconstruction of the Shoulder Girdle - scapular massive allograft.- 37.   Implant Reconstruction of the Shoulder Girdle: scapular prosthesis.-Part 12: Proximal humerus.- 38.   Proximal Humerus, Biological Reconstruction.- 39.   Claviculo-Pro-Humero reconstruction following proximal humeral resection for sarcoma.- 40.   Biological Reconstruction of the Proximal Humerus - III   massive allograft & inlaid free vascular fibula with epiphyseal transfer.- 41.   Implant Reconstruction of the Proximal Humerus.- 42.   Implant Reconstruction of the Proximal Humerus - II: reverse prosthesis.- Part 13: Humeral diaphysis.- 43.   Biological Reconstruction of the Humeral Diaphysis: irradiated autograft.- 44.   Implant Reconstruction of the Humeral Diaphysis: total humerus prosthesis.- Part 14: Distal humerus & elbow.- 45.   Implant Reconstruction of the Distal Humerus & Elbow  - modular prosthesis.- Part 15: Forearm, wrist & hand.- 46.   Biological Reconstruction of the Forearm, Wrist & Hand - I: free vascular fibula.- 47.   Biological Reconstruction of the Forearm, Wrist & Hand - II: transposition of the distal ulna.- 48.   Implant Reconstruction of the forearm, wrist, and hand - Distal Radius Endoprosthesis.- Part 16: Complications of orthopedic oncologic  reconstructions.- 49.   Biological.- 50.   Implant.