Thalassemia, An Issue of Hematology/Oncology Clinics of North America -

Thalassemia, An Issue of Hematology/Oncology Clinics of North America

Buch | Hardcover
240 Seiten
2023
Churchill Livingstone (Verlag)
978-0-443-18320-1 (ISBN)
107,20 inkl. MwSt
In this issue of Hematology/Oncology Clinics, guest editors Drs. Edward J. Benz, Jr. and Vijay G. Sankaran bring their considerable expertise to the topic of Thalassemia. Top experts in the field provide an overview of the history, epidemiology, pathogenic mechanisms, and clinical management of the thalassemia syndromes.

Contains 16 practice-oriented topics including molecular basis and genetic modifiers of thalassemia; fetal hemoglobin in thalassemia; clinical complications and their management; iron chelation in thalassemia; fertility and pregnancy in women with transfusion-dependent thalassemia; gene therapy and genome editing in thalassemia; emerging medical therapies for thalassemia; and more. 


Provides in-depth clinical reviews on thalassemia, offering actionable insights for clinical practice. 


Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews. 

Introduction to the Thalassemia Syndromes: Molecular Medicine's Index Case
The Need for Translational Epidemiology in Beta Thalassemia Syndromes:A Thalassemia International Federation Perspective
Molecular Basis and Genetic Modifiers of Thalassemia
Fetal Hemoglobin Regulation in Beta-Thalassemia
Clinical Classification, Screening, and Diagnosis in Beta-Thalassemia and Hemoglobin E/Beta-Thalassemia
The Clinical Phenotypes of Alpha Thalassemia
Pathogenic Mechanisms in Thalassemia I: Ineffective Erythropoiesis and Hypercoagulability
Pathogenic Mechanisms in Thalassemia II: Iron Overload
Clinical Complications and Their Management
Clinical Challenges with Iron Chelation in Beta Thalassemia
Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia
Hematopoietic Stem Cell Transplantation in Thalassemia
Gene Therapy and Gene Editing for b-Thalassemia
Emerging Therapies in b-Thalassemia

Erscheinungsdatum
Reihe/Serie The Clinics: Internal Medicine
Verlagsort London
Sprache englisch
Maße 152 x 229 mm
Gewicht 520 g
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
ISBN-10 0-443-18320-1 / 0443183201
ISBN-13 978-0-443-18320-1 / 9780443183201
Zustand Neuware
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