Endocrine Disruption

Biological bases for health effects in wildlife and humans

David O. Norris, James A. Carr (Herausgeber)

Buch | Hardcover

496 Seiten

2005
Oxford University Press Inc (Verlag)
978-0-19-513749-1 (ISBN)

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Addresses the biological effects of the large number of compounds that have been recognized as endocrine disrupters. This book presents the relevant fundamentals of the endocrine systems of animals and humans, the toxicology, developmental toxicology, ecology, and risk assessment methods, and lays out the state of understanding for the field.

This book addresses the biological effects of the large number of compounds that have been recognised as endocrine disrupters. These compounds have been found to persist as pollutants in the environment, and have been blamed for causing developmental disorders and/or fertility problems in fish, amphibians, reptiles, birds, and humans. The book presents the relevant fundamentals of the endocrine systems of animals and humans, the toxicology, developmental toxicology, ecology, and risk assessment methods, and lays out the current state of understanding for the whole field, organized by the classes of compounds that have been identified as endocrine disrupters.

Part I. Vertebrate Chemical Regulation
1.: David O. Norris and James A. Carr: Introduction to Endocrinology
2.: Miles Orchinik and Catherine Propper: Hormone Action on Receptors
3.: James A. Carr and David O. Norris: The Hypothalamus-Pituitary Axis
4.: James A. Carr and David O. Norris: The Thyroid Gland
5.: James A. Carr and David O. Norris: The Adrenal Glands
6.: James A. Carr and David O. Norris: The Gonads
Part II. Toxicology and Risk Assessment
7.: Richard L. Dickerson and Ernest E. Smith: Introduction to the Science of Toxicology
8.: Kenneth R. Dixon and Clyde F. Martin: Probablistic Risk Assessment
9.: Lynn Frame and Richard L. Dickerson: Fish and Wildlife as Sentinels of Environmental Contamination
Part III. Representative EDCs in Animals
10.: Mary K. Walker: Polychlorinated Dibenzo-p-Dioxins: Potential Mechanisms and Risk as Endocrine Disruptors
11.: John P. Giesy, K. Kannan, Alan L. Blankenship, Paul D. Jones, and J.L. Newsted: Toxicology of PDBs and Related Compounds
12.: Louis J. Guillette, Jr., Stefan A.E. Kools, Mark P. Gunderson, and Dieldrich S. Bermudez: DDT and Its Analogues: New Insights into Their Endocrine-Disrupting Effects on Wildlife
13.: Alice Hontela and Alexandra Lacroix: Heavy Metals
14.: Werner Kloas: Effects of Alkyphenolic Compounds on Wildlife
15.: Alan M. Vajda and David O. Norris: Endocrine-Active Phytochemicals: Environmental Signaling Context and Mechanisms
16.: Timothy S. Gross and R. Heath Rauschenberger: Triazines
Appendices

Erscheint lt. Verlag	20.10.2005
Zusatzinfo	48 tables, 91 line illus.
Verlagsort	New York
Sprache	englisch
Maße	234 x 163 mm
Gewicht	816 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
	Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Ökologie / Naturschutz
	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	0-19-513749-3 / 0195137493
ISBN-13	978-0-19-513749-1 / 9780195137491
Zustand	Neuware