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The Non-Hodgkin's Lymphomas, 2Ed

Buch | Hardcover
1168 Seiten
1996 | 2nd New edition
Hodder Arnold (Verlag)
978-0-340-55793-8 (ISBN)
246,90 inkl. MwSt
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Non-Hodgkin's lymphomas are a group of blood malignancies associated mostly with children, and on the increase in the West, having previously only affected Africa and the Middle East. This revised and updated edition has been produced to keep pace with this rapidly developing field.
In its first edition, this book established itself as the classic text on Non-Hodgkin's Lymphomas, a group of blood malignancies associated most commonly with children and now on the increase in the West.



The success of the first edition lay in the skill with which Dr Magrath integrated the molecular biology of cancer with the clinical management. In this second, considerably expanded edition approximately two-thirds of the text and illustrations are new, and the remaining third has been extensively revised, with areas of controversy given special consideration. In particular, detailed information is now provided on recently defined sub-types of lymphoma which were mentioned only briefly in the first edition.

Part I Evolution of present concepts - Introduction
Historical perspective
Part II Pathology - Histopathology and immunopathology
The role of molecular analysis in lymphoma diagnostics
Borderlands of pathological entities
Part III Epidemiology and pathogenesis - Epidemiology of Non-Hodgkin's Lymphoma
Ontogeny, distribution and functions of T Lymphocytes
Ontogeny and functions of B lymphocytes
Lymphokines and interleukins
Molecular genetics of lymphomagenesis (An overview) Cytogenetics of the NHLs
Epstein-Barr Virus and NHLs
Lymphoproliferations associated with human oncoretroviruses: Human T cell leukemia-lymphoma virus types I and II
Pathogenesis of low grade B cell lymphomas
Pathogenesis of intermediate grade B cell lymphomas
Pathogenesis of small noncleaved cell lymphomas
Molecular pathogenesis of T cell lymphomas
Pathogenesis of Ki-1 positive lymphomas
Lymphoproliferative disorders associated with primary immunodeficiencies
Pathology and the pathogenesis of NHLs associated with HIV infection
Lymphomas of mucosa-associated lymphoid tissue
Intestinal lymphoma and heavy chain disease
Part IV Presentation, staging and follow-up studies - Presenting features
Staging systems and staging investigations
Radionuclide imaging
Other imaging techniques in NHLs
Part V General principles of management - Complications in the management of NHLs
Principles of chemotherapy
Role of colony stimulating factors in therapy
Radiation therapy in the NHLs
The role of surgery
Biological response modifiers
Management of recurrent or refractory lymphomas
Bone marrow transplantation for NHLs
Prognostic factors in NHL
Late effects of treatment for NHL
Part VI Clinical features and management of NHLs - Small non-cleaved cell lymphomas
Lymphoblastic lymphomas
Large cell lymphomas in children
Diffuse small cell lymphomas
Follicular lymphomas
Diffuse aggressive lymphomas in adults
Cutaneous T cell lymphomas
Other peripheral T cell lymphomas
Lymphoproliferative disorders in immunocompromised patients
Clinical aspects of HIV-associated lymphomas
Treatment of malignant neoplasms of the mucosa-associated lymphoid tissues
Extranodal lymphomas
Part VII Special topics - Lymphomas in developing countries
Important topics for future clinical trials
Exploitation of genetic abnormalities in the development of novel treatment strategies for hematological malignancies.

Erscheint lt. Verlag 24.12.1996
Verlagsort London
Sprache englisch
Themenwelt Medizinische Fachgebiete Innere Medizin Endokrinologie
Medizinische Fachgebiete Innere Medizin Hämatologie
Medizin / Pharmazie Medizinische Fachgebiete Onkologie
ISBN-10 0-340-55793-1 / 0340557931
ISBN-13 978-0-340-55793-8 / 9780340557938
Zustand Neuware
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