Intensive Care Medicine

Sepsis Mediators. Update on CD14, LBP, and Toll-like Receptors in Acute Infections. Alcohol Abuse: A Major Contributing Factor to Post-burn/trauma Immune Complications. Redox Imbalance in Sepsis and the Systemic Inflammatory Response Syndrome.- Cellular Alterations in Sepsis. The Role of Leptin in Sepsis. Role of Peroxisome Proliferator-activated Receptor-alpha in Inflammation and Septic Shock. Influence of Acid-base Balance in Patients with Sepsis. Muscle Failure in Septic Patients.- Nitric Oxide Metabolism. Role of Neuronal Nitric Oxide Synthase in Cardiopulmonary Lesions of Sepsis. Asymmetrical Dimethylarginine in Critical Illness: A New Causative Factor in Organ Failure?.- Relative Adrenal Insufficiency. The Role of the Hypothalamic-Pituitary-Adrenal (HPA)-axis in Severe Sepsis and Critical Illness. Assessment of Adrenocortical Function in Critical Illness: The Debate Continues. Low Dose Corticosteroids in Septic Shock.- Resuscitation. Emergency Ventilatory Management as a Detrimental Factor in Resuscitation Practices and Clinical Research Efforts. Shock: Pathogenesis and General Principles of Management.- Sepsis Therapies. Goal-directed Hemodynamic Therapy in the ICU: Application and Possible Mechanism of Therapeutic Effect. Coupled Plasma Filtration Adsorption.- Additional Therapeutic Agents. Role of Vasopressin and Terlipressin in the setting of Systemic Inflammation. N-Acetylcysteine: Always the Bridesmaid….?. Prostaglandin I2: More than a Vasodilator and Inhibitor of Platelet Aggregation?.- Antimicrobial Strategies. Antibiotic Therapy for Sepsis, Severe Sepsis, and Septic Shock: The "Tarragona" Strategy. Empiric Antibiotic Therapy In Life-threatening Infections: The "Varese" Approach. The Spectrum of Invasive Aspergillosis in the ICU: Not just for Hematology Patients. Herpes Simplex Virus Type 1 Infections of the Respiratory Tract in Critically ill Patients.- Respiratory Failure: Basic Mechanisms. Coagulation and Fibrinolysis in Acute Lung Injury and Pneumonia. Matrix Metalloproteases: A Potential Role in the Pathogenesis of ARDS. The Immune Response to Resistive Breathing: Implications for Respiratory Failure.- Respiratory Failure: Clinical Aspects. Respiratory Function in Morbidly Obese Subjects. Respiratory Failure and Diaphragm Function. SARS and Critical Care Medicine: The Toronto Experience.- Mechanical Ventilation. Cough Assistance in Mechanically Ventilated Neuromuscular Patients. Over-humidification: An Under-recognized Problem. Weaning and Withdrawing Mechanical Ventilatory Support.- VILI, VALI, and VASI. The Role of Cytokines in VALI and VASI. Role of G-proteins in VILI. Effect of Mechanical Ventilation on Pulmonary and Peripheral Immune Function.- ALI/ARDS. Helmet CPAP in Acute Respiratory Failu