Nuclear Medicine in Clinical Diagnosis and Treatment - Peter J. Ell, Sam Gambhir

Nuclear Medicine in Clinical Diagnosis and Treatment

2-Volume Set
Buch | Hardcover
1950 Seiten
2004 | 3rd Revised edition
Churchill Livingstone (Verlag)
978-0-443-07312-0 (ISBN)
569,95 inkl. MwSt
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Intended for those involved in the practice of nuclear medicine, this edition features the advances in diagnostic and therapeutic modalities used in the detection and treatment of cancer, heart disease, neurologic disorders, trauma and other diseases. It covers the major body systems and organs in which nuclear medicine procedures are used.
This definitive and comprehensive 2 volume text-reference book is essential reading for those who are primarily involved in the practice of nuclear medicine. Over 180 contributors, all of them internationally recognized authorities, focus on current and newly available radionuclide techniques and directly apply them to clinical practice. Covering all of the major body systems and organs in which nuclear medicine procedures are used, the book takes a disease oriented approach and this new edition features the latest advances in diagnostic and therapeutic modalities used in the detection and treatment of cancer, heart disease, neurologic disorders, trauma and other common and less common diseases. There are major revisions/ new chapters in the areas of brain imaging, movement disorders, stroke, lymphoma therapy, bone density, non-neurologic drug discovery, molecular imaging, cost/benefit analysis.

Features over 4,400 high quality images depicting a full range of both common and rare diseases and abnormalities.
Emphasizes how to perform and interpret a test rather than the technical aspects of the procedure, and focuses on how to solve the diagnostic problems that occur in day-to-day practice.
Addresses practical considerations such as image interpretation, image optimization techniques, and pitfalls in image acquisition, and interpretation.
Offers state-of-the art global perspectives from an international team of editors and authors.



Provides completely revised and thoroughly up-to-date coverage in every chapter.
Introduces a new co-editor-Dr Sam Gambhir, who provides new perspectives on the field's hottest developments.
Presents expanded coverage of tumor diagnosis and therapy · cardiac nuclear imaging · and radionuclide imaging of neurologic and psychiatric disorders.
Features brand-new chapters on lymphoma therapy · PET imaging · sentinel lymph node biopsy · gated SPECT · multi-modality imaging · molecular imaging · drug discovery · cost/benefit analysis · and bone density.
Incorporates full-color images throughout the text.

Section 1: Nuclear medicine in tumor diagnosis and therapy

Part A: Diagnosis

1.Tumor-seeking radiopharmaceuticals: nature and mechanisms

2Radionuclide imaging of hepatic tumors

3PET in lymphoma and malignant melanoma

4Parathyroid imaging

5Adrenocortical scintigraphy

6Gallium scintigraphy in tumor diagnosis and management

7Thallium-201 chloride: a tumor imaging agent

8MIBG in the diagnosis of neuroendocrine tumors

9Peptide receptor scintigraphy in oncology

10The diagnostic role of radiolabeled antibodies in cancer

11Cancer cell biology basis for nuclear oncology

12Differentiated thyroid carcinoma

13Medullary thyroid cancer

14Breast scintigraphy

15Pediatric tumors

16Functional analysis of cancer therapy effects in other organs

17The use of intraoperative probes in surgical oncology

18The sentinel lymph node in surgical oncology

19FDG PET Imaging of Head and Neck Cancer

20External Beam Radiotherapy Treatment Planning with PET

21PET in aerodigestive tumors

22PET in gynecological tumors (breast, cervical and ovarian)

23Nuclear medicine imaging in pediatric oncology

24Positron Emission Tomography (PET) in genitourinary tumors: prostate, bladder, testicular and renal cancer

25Future clinical applications of PET (amino acid and nucleoside imaging)

26PET imaging of brain tumors


Section 1: Nuclear medicine in tumor diagnosis and therapy

Part B: Radionuclide therapy

27Principles of radionuclide therapy

28Dosimetric and radiobiological considerations: The MIRD concept

29Dosimetric and radiobiological considerations: Patient-individual dosimetry

30Radioiodine therapy of the thyroid: Treatment of benign thyroid diseases

31Radioiodine therapy of the thyroid: Treatment of thyroid malignancies

32Phosphorus-32 therapy in myeloproliferative disorders

33Palliation of bone pain

34Radioimmunotherapy of hematologic neoplasms

35Radioimmunotherapy of solid tumors

36MIBG therapy

37Receptor-targeted radiopeptide therapy

38Use of radiolipiodol in the treatment of hepatic tumours

39Alternative approaches to targeting therapy

40New developments: Nuclear gene therapy

41Atlas 1: PET and PET/CT

42Atlas 2: SPET and SPET/CT


Section 2: Nuclear medicine in disorders of bones and joints

43Bone scintigraphy: the procedure and interpretation

44Evaluation of primary bone tumors

45The evaluation of malignancy: metastatic bone disease

46Assessment of infection

47Radionuclide assessment of the painful joint prosthesis

48Vascular manifestations

49Bone scintigraphy in trauma

50Bone scintigraphy in sports medicine

51Growth and metabolic disorders

52Arthritis: current status of scintigraphy and future trends

53Radiation synovectomy


Section 3: Quantitative studies of gastrointestinal function

54Salivary gland disorders

55Esophageal function (transport and motility)

56Gastric motility

57Intestines: evaluation of absorption

58Studies of small bowel and colonic transit

59Hepatobiliary function: biliary kinetics

60Scintigraphic measurement of hepatic function


Section 4: Nuclear medicine in acute care

61Nuclear cardiology and cardiac transplantation

62Cardiovascular conditions: venous thrombosis

63Pulmonary embolism

64Non-embolic disease of the lungs

65Gastrointestinal bleeding

66Cholescintigraphy

67Neonatal hyperbilirubinemia

68Nuclear medicine in acute care of neurological patients

69Radiolabeled agents for the localization of infection and inflammation

70Undiagnosed fever

71Inflammatory bowel disease

72Nuclear imaging in cardiovascular infection and cardiac transplant rejection

73The immunocompromised patient


Section 5: Nuclear cardiology

74Radiopharmaceuticals for the study of the heart

75Radionuclide ventriculography and the assessment of impaired ventricular function

76Infarct avid imaging and myocardial perfusion scintigraphy techniques using single photon radiotracers

77Cardiac positron emission tomography

78Cardiac stress

79The detection of coronary artery disease

80Assessment of prognosis in patients with known or suspected coronary artery disease

81Assessment after myocardial revascularization

82Assessment of myocardial viability in dysfunctional myocardium

83Myocardial infarction: the assessment of thrombolysis

84Congenital heart disease

85Single-photon imaging of myocardial metabolism: the role of iodine 123 fatty acids and fluorine-18 deoxyglucose

86Clinical applications of PET

87Myocardial innervation: imaging and quantification

88Nuclear medicine techniques in the assessment of human thrombosis and atheroma


Section 6: Nuclear medicine in neurological and psychiatric diagnosis

89The blood-brain barrier

90Lipophilic tracers: the amines

91Lipophilic tracers for the study of regional cerebral blood flow

92Ligands for neuroreceptor imaging by positron or single photon emission tomography

93PET tracers for brain scanning

94Neuroactivation

95Image analysis in brain SPECT and PET

96SPECT brain imaging in cerebrovascular disease

97Nuclear medicine in the management of a patient with epilepsy

98Nuclear medicine and the management of patients with Parkinson's movement disorders

99Anxiety disorders and affective disorders

100Addictions

101The management of patients with schizophrenia

102PET and SPECT imaging in evaluating Alzheimer's disease and related dementias

103Nuclear medicine and drug studies in the brain

104Cerebrospinal fluid physiology, clearance flow studies and cerebrospinal fluid shunt studies

105Atlas 3: PET brain atlas


Section 7: Nuclear medicine in renal disorders

106Overview of renal nuclear medicine

107Radiopharmaceuticals: their intrarenal handling and localization

108Dynamic static renal imaging

109Quantitative evaluation of clearance

110Measurement and interpretation of renal transit times

111The role of PET in renal nuclear medicine

112Renal infection

113Pediatric aspects of radionuclides in nephrourology

114Nuclear medicine in the clinical diagnosis and treatment of obstructive uropathy

115Vascular disorders, with emphasis on hypertension

116Renal failure

117Space-occupying lesions and trauma

118Renal transplant evaluation

119The genital tract


Sction 8: Basic sciences

120Fundamental molecular/cell biology

121Radioisotope production

122Radiochemistry

123Radiopharmacy

124Basic physics and detection of radiation

125Nuclear medicine imaging instrumentation

126Nuclear medicine computers: Basic principles

127Nuclear medicine computers: Applications

128Single photon emission computed tomography (SPECT)

129Positron emission tomography (PET)

130Primer on molecular imaging

131Radiation protection and dosimetry in clinical practice

132Clinical decision making: an introductory, quantitative approach to diagnostic investigations

133ecision analysis fundamentals

Erscheint lt. Verlag 15.7.2004
Verlagsort London
Sprache englisch
Themenwelt Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Neuroradiologie
Medizinische Fachgebiete Radiologie / Bildgebende Verfahren Nuklearmedizin
Studium 2. Studienabschnitt (Klinik) Anamnese / Körperliche Untersuchung
ISBN-10 0-443-07312-0 / 0443073120
ISBN-13 978-0-443-07312-0 / 9780443073120
Zustand Neuware
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