The Immune System - Peter Parham

The Immune System

(Autor)

Buch | Softcover
456 Seiten
2004 | 2nd New edition
Garland Publishing Inc (Verlag)
978-0-8153-4093-5 (ISBN)
58,60 inkl. MwSt
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The new edition of The Immune System has been thoroughly updated throughout. This book includes increased emphasis on genetics, the human immune system and the treatment of innate immunity, particularly the mucosal system.
The Immune System, Second Edition has been designed for use in immunology courses for undergraduate, medical, dental, and pharmacy students. This class-tested and successful textbook synthesizes the established facts of immunology into a comprehensible, coherent, and up-to-date account of how the immune system works, rather than presenting immunology as a chronology of experiments and discoveries. Emphasizing the human immune system the text has been designed to break down the barriers which often divide basic and clinical immunology. The reader-friendly text, section and chapter summaries, and full-color illustrations make the book accessible and easily understandable to students. The Immune System is adapted from Immunobiology by Janeway, Travers & Walport.

Chapter 1: Elements of the Immune System and their Roles in Defense. Defenses facing invading pathogens. Principles of adaptive immunity. Chapter 2: Antibody Structure and the Generation of B-Cell Diversity. The structural basis of antibody diversity. Generation of immunoglobulin diversity in B cells before encounter with antigen. Diversification of antibodies after B cells encounter antigen. Chapter 3: Antigen Recognition by T Lymphocytes. T-cell receptor diversity. Antigen processing and presentation. The major histocompatibility complex. Chapter 4: The Development of B Lymphocytes. The development of B cells in the bone marrow. Selection and further development of the B-cell repertoire. Chapter 5: The Development of T Lymphocytes. The development of T cells in the thymus. Positive and negative selection of the T-cell repertoir. Chapter 6: T-Cell Mediated Immunity. Activation of naive T cells on encounter with antigen. The properties and functions of effector T cells. Chapter 7: Immunity Mediated by B Cells and Antibodies. Antibody production by B lymphocytes. Antibody effector functions. The antigen-antibody mediated pathway of complement activation. Chapter 8: The Body's Defenses Against Infection. Innate immunity. Adaptive immune responses to infection. Immunological memory and the secondary immune response. Chapter 9: Failures of the Body's Defenses. Evasion and subversion of the immune system by pathogens. Inherited immunodeficiency diseases. Acquired Immune Deficiency Syndrome. Chapter 10: Over-reactions of the Immune System. Type I hypersensitivity reactions. Types II, III, and IV hypersensitivity reactions. Chapter 11: Disruption of Healthy Tissue by the Immune Response. Autoimmune diseases. Genetic and environmental factors which predispose to autoimmune disease. Chapter 12: Manipulation of the Immune Response. Prevention of infectious disease by vaccination. Transplantation of tissues and organs. Cancer and its interactions with the immune system.

Sprache englisch
Maße 216 x 279 mm
Gewicht 1043 g
Themenwelt Studium Querschnittsbereiche Infektiologie / Immunologie
ISBN-10 0-8153-4093-1 / 0815340931
ISBN-13 978-0-8153-4093-5 / 9780815340935
Zustand Neuware
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