The Politics of Personalised Medicine
Pharmacogenetics in the Clinic
Seiten
2004
Cambridge University Press (Verlag)
978-0-521-84177-1 (ISBN)
Cambridge University Press (Verlag)
978-0-521-84177-1 (ISBN)
Applies a social science perspective to exploring issues arising in clinical practice as a result of drug development linked to genetic testing. These include the social context within which new drugs are trialled, attitudes of the clinicians asked to administer them, expectations of clinicians and patients and associated ethical issues.
Pharmacogenetics, the use of genetic testing to prescribe and develop drugs, has been hailed as a revolutionary development for the pharmaceutical industry and modern medicine. Supporters of 'personalised medicine' claim the result will be safer, cheaper, more effective drugs, and their arguments are beginning to influence policy debates. Based on interviews with clinicians, researchers, regulators and company representatives, this book explores the impact of pharmacogenetics on clinical practice, following two cases of personalised medicine as they make their way from the laboratory to the clinic. It highlights the significant differences between the views of supporters of pharmacogenetics in industry and those who use the technology at the clinical 'coal face'. Theoretically, this work builds on the developing area of the sociology of socio-technical expectations, highlighting the way in which promoters of new technologies build expectations around it, through citation and the creation of technological visions.
Pharmacogenetics, the use of genetic testing to prescribe and develop drugs, has been hailed as a revolutionary development for the pharmaceutical industry and modern medicine. Supporters of 'personalised medicine' claim the result will be safer, cheaper, more effective drugs, and their arguments are beginning to influence policy debates. Based on interviews with clinicians, researchers, regulators and company representatives, this book explores the impact of pharmacogenetics on clinical practice, following two cases of personalised medicine as they make their way from the laboratory to the clinic. It highlights the significant differences between the views of supporters of pharmacogenetics in industry and those who use the technology at the clinical 'coal face'. Theoretically, this work builds on the developing area of the sociology of socio-technical expectations, highlighting the way in which promoters of new technologies build expectations around it, through citation and the creation of technological visions.
Adam Hedgecoe is Lecturer at the Department of Sociology, University of Sussex. He has published in Science, Technology and Human Values, Social Studies of Science, Sociology of Health and Illness, and Bioethics.
1. Personalised medicine - a revolution in health care; 2. Pharmacogenetics, expectation and promissory science; 3. Genetics, moral risk and professional resistance; 4. Clinical resistance to Alzheimer's pharmacogenetics; 5. Research, industry and pharmacogenetic literacy; 6. Engineering the clinic - getting personalised medicine into practice; 7. The fourth hurdle - cost effectiveness and the funding of pharmacogenetics; 8. Disappointment and disclosure in the pharmacogenetic clinic; 9. The personalised is political.
Erscheint lt. Verlag | 2.12.2004 |
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Reihe/Serie | Cambridge Studies in Society and the Life Sciences |
Zusatzinfo | 1 Line drawings, unspecified |
Verlagsort | Cambridge |
Sprache | englisch |
Maße | 160 x 236 mm |
Gewicht | 465 g |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
ISBN-10 | 0-521-84177-1 / 0521841771 |
ISBN-13 | 978-0-521-84177-1 / 9780521841771 |
Zustand | Neuware |
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