Cardiac Gene Therapy

Updates on Cardiac Gene Therapy Research and Methods: Overview of Cardiac Gene Therapy.- Tough Decoy-Mediated Cardiac Gene Suppression.- Direct Reprogramming of Adult Human Cardiac Fibroblasts into Induced Cardiomyocytes using miRcombo.- CRISPR/Cas9 Gene Editing of RYR2 in Human iPSC Derived Cardiomyocytes to Probe Ca2+ Signaling Aberrancies of CPVT Arrhythmogenesis.- Enhancing Cardiomyocyte Transcription using In Vivo CRISPR/Cas9 Systems.- AAV Mediated Somatic Gene Editing for Cardiac and Skeletal Muscle in a Large Animal Model.- Optimization of Synthesis of Modified mRNA.- Design and Production of Heart Chamber-Specific AAV9 Vectors.- Generation of Atrial-Specific Construct using Sarcolipin Promoter Associated CRM4 Enhancer.- Cardiac Targeted Adeno-Associated Virus Injection in Rats.- Cardiac Gene Delivery in Large Animal Models-Antegrade Techniques.- Locked Nucleic Acid AntimiR Therapy for the Heart.- Cardiac Gene Delivery in Large Animal Models: Selective Retrograde Venous Injection.- Endocardial Gene Delivery using NOGA Catheter System.- Surgical Methods for Cardiac Gene Delivery in Large Animals.- Atrial Gene Painting in Large Animal Model of Atrial Fibrillation.- Stent-Based Gene Delivery for Coronary Disease.- Selective Anti-AAV Antibody Depletion by Hemapheresis and Immunoadsorption.- Ex Vivo Delivery of Viral Vectors by Organ Perfusion for Cardiac Transplantation Gene Therapy.- Intra-Airway Gene Delivery for Pulmonary Hypertension in Rodent Models.- Endo-Bronchial Gene Delivery for Pulmonary Hypertension in a Large Animal Model.- Cell-Based Determination of Neutralizing Antibodies against Adeno-Associated Virus in Cardiac Gene Therapy.- Left Ventricular Pressure Volume Assessment Using Carotid Artery Access in the Rat.- Assessing the Effect of Cardiac Gene Therapy using Catheter-Based Pressure-Volume Measurement in Large Animals.- ELIspot Assay for Gene Therapy in Large Animal Studies.- Assessing Recombinant AAV Shedding after Cardiac Gene Therapy.