Cardiopulmonary Bypass

After finishing the Medicine Faculty of Istanbul University in 1990, Prof Kırali fulfilled MD, MSc medical mandatory service duty and began his residency training in Koşuyolu Heart and Research Hospital in 1992. Following 5 years of assistant education, he was in England and the USA for education and training in 1998. He performed his work mostly in the field of videoscopic and minimally invasive cardiac surgery, and he became a consultant cardiovascular surgeon in 1998, Assistance Professor in 1999, Associate Professor in 2002, and chief in 2005 at the same hospital. Over the last 20 years, he has focused his scientific interests on topics related to cardiovascular repairs requiring special experience. With his expertise in coronary artery surgery, minimal invasive cardiac surgery, valve repair, and aortic root surgery, he has established new methods for awake coronary bypass revascularization, new surgical approach for AVR during first and re-operations, aortic valve sparing procedure, and radiofrequency ablation. He is the pioneer of awake complete CABG with BIMA and has also developed a new aortotomy incision technique for all kinds of aortic valvular or subvalvular interventions during first and re-operations, which simplifies the procedure with/without aortic valve insertion. He has experience on cardiac failure during ECMO and developed a specific design for recovery. He has been the director of transplantation department since 2015. Prof. Joseph Coselli is the chief Professor of Surgery, of the Division of Cardiothoracic Surgery and the Executive vice-chair of Michael E. DeBakey Department of Surgery at Baylor College of Medicine, United States. He has specialized in the evaluation and treatment of aortic disease, including the aortic valve and root, the aortic arch, and the thoracoabdominal aorta, using open surgical and endovascular techniques. In 40 years of service, he has performed more than 10,500 aortic repairs, including more than 3700 repairs of thoracoabdominal aortic aneurysms, for which he is world-renowned. Prof Kalangos MD, PhD is a Greek-Swiss cardiovascular surgeon and Philanthropist. He currently serves as the Chairman of the Department of Pediatric and Congenital Cardiovascular Surgery at Mitera Hospital in Athens and as a full Professor of Pediatric Cardiovascular Surgery at Koc University Hospital in Istanbul, Türkiye. He is the President and founder of the Kalangos Foundation, the President and founder of the Global Forum on Humanitarian Medicine in Cardiology and Cardiac Surgery and the President and co- founder of Global Heart Network. He was the former President of the World Society of Cardiovascular and Thoracic Surgeons in 2014-2015 and is currently the treasurer of the society. He is also the inventor of the Kalangos biodegradable annuloplasty Rin. This device is being used in the repair of the mitral and tricuspid valves especially in children.

VOLUME I

PART I. Extracorporeal Life Support

Editorial

Kaan Kırali

Introduction: Surgical Perspective

Marko Turina

Introduction: Perfusional Perspective

Gerard J. Myers

PART II. Artificial Circulation and Respiration

1. Development of Extracorporeal Circulation

Steven Tsui and Ismail Vokshi

2. Future Artificial Surface Physiology

Manoj Myneni and Keshava Rajagopal

3. Future Artificial Heart

O.H. Frazier

4. Future Artificial Lung

Justyna Swol

5. Future Noninvasive Monitoring

Silvia Mariani, Maria De Piero and Axel Haveric

6. 3D Printing for Artificial Physiology

Zhonghua Sun

7. Advances for Artificial Circulation Guidelines

Kaan Kırali

PART III. Cardiopulmonary Bypass (CPB)

8. Basics of Extracorporeal Circulation

Vipin Zamvar and Peter Lang

9. Pathophysiology of Cardiopulmonary Bypass

Kaan Kırali, Davut Çekmecelioğlu, Tanıl Özer, Tolga Baş and Hülya Yük

10. Microcirculation During Cardiopulmonary Bypass

Thanos Athanasiou, Maria Fergadi and Dimitrios Magouliotis

11. Standards for Cardiopulmonary Bypass

David Fitzgerald and Justin Resley

12. Mechanical Pumps for Cardiopulmonary Bypass

Georg Maximilian Wieselthaler

13. Oxygenators for Cardiopulmonary Bypass

Korneel Vandewiele and Stefaan Bouchez

14. Cannulations for Cardiopulmonary Bypass

Gino Gerosa, Assunta Fabozzo and Chiara Tessari

15. Anesthesia During Cardiopulmonary Bypass

Antonio Pisano, Carolina Soledad Romero García, Nicola Galdieri and Giovanni Landoni

16. Monitoring During Cardiopulmonary Bypass

Kaan Kırali, Mustafa EMRE Gürcü, Pınar Karaca Baysal and Özlem Oğuzhan

17. Transesophageal Echocardiography During Cardiopulmonary Bypass

Federico Pappalardo, Giulia Maj and Stephanie Bertolin

18. Hemostasis During Cardiopulmonary Bypass

Giuseppe G. Faggian, Francesco Onorati, Ilaria Tropea, Annalisa Bernabei and Alessandra Francica

19. Myocardial Preservation During Cardiopulmonary Bypass

Kaan Kırali, Hakan Hançer, Taylan Adademir, Tolga Baş and Mine Şimşek

20. Cerebral Preservation During DHCA in Cardiopulmonary Bypass

Shahzad G. Raja

PART IV. Special Cardiopulmonary Bypass

21. Cardiopulmonary Bypass in Pregnancy

Hartzell Schaff and Sri Harsha Patlolla

22. Cardiopulmonary Bypass in Neonates and Infants

Akif Undar, Ryan M. Holcomb, Krishna Patel and Yongwook Dan

23. Cardiopulmonary Bypass in Pediatrics

Afksendiyos Kalangos and Nataliia Shatelen

24. Cardiopulmonary Bypass in Thoracic Aortic Surgery

Davut Çekmecelioğlu, Kathleen Kibler, Vicente Orozco-Sevilla, and Joseph S. Coselli

25. Cardiopulmonary Bypass in Lung Transplantation

Alexander Sasha Krupnick, Aakash Shah and Joshua L. Leibowitz

26. Cardiopulmonary Bypass in Non-Cardiac Thoracic Surgery

Başar Sareyyüpoğlu, Magdy M. El-Sayed Ahmed and Mathew Thomas

PART V. Special Situations for Perfusion

27. Perfusion Ethics, Accreditation and Education

David Fitzgerald and David Fisher Jr

28. Perfusion Training

Sven Maier and Christoph Benk

29. Perfusion Management

Filip De Somer

30. Perfusion Accidents Management

Carrel Thierry, Erich Gygax and Sarah Longnus-Henning

31. Perfusion Separation Challenge

Vladimir Lomivorotov and Ludmila Lomivorotova

32. Perfusion for HIPEC

Mustafa Duman, Erdal Polat, Mehmet Can, Kaan Kırali and Ercan Ersoy

Part VI. Miniaturizing Cardiopulmonary Bypass

33. Miniaturizing Cardiopulmonary Bypass (MiCPB)

Kyriakos Anastasiadis, Polychronis Antonitsis, Kyriakos Anastasiadis, Helena Argiriadou and Apostolos Deliopoulos

34. MiCPB in Cardiac Surgery

Konstantinos S. Mylonas and Dimitrios V. Avgerinos

35. MiCPB in Heart Valve Surgery

Kaan Kırali

36. MiCPB in Robotic Cardiac Surgery

Michael J. Bates, W. Douglas Boyd, L. Wiley Nifong and Randolph Chitwood

37. MiCPB in Pediatrics

Giovanni Battista Luciani, Alessio Rungatscher, Daniele Linardi and Stiljan Hoxha

Part VII. Organ Injury and Protection in Cardiopulmonary Bypass

38. Metabolic Aspects in Cardiopulmonary Bypass

John R. Cooper Jr, Katherine Gordon and Claudia Yu Yao Wei

39. Inflammatory Injury in Cardiopulmonary Bypass

Shahzad G. Raja

40. Inflammatory Protection and Immune Support for Cardiopulmonary Bypass

Shahzad G. Raja

41. Lung Injury in Cardiopulmonary Bypass

Stephen C. Clark and Vikrant Pathania

42. Pulmonary Protection and Respiratory Support for Cardiopulmonary Bypass

Kaan Kırali, Halide Oğuş, Mustafa Mert Özgür and Uğur Eke

43. Brain Injury in Cardiopulmonary Bypass

Michael P. Vallely, Fabio Ramponi, Kaye Hon, Michael Seco, John D. Puskas, Jonathon Fanning, Stuart Grieve, Paul Bannon and Leonard Kritharides

44. Cerebral Protection and Neurologic Support

John M. Murkin and Agya Boakye Atonsah Prempeh

45. Kidney Injury in Cardiopulmonary Bypass

Eduard Quintana, Cristina Ibáñez, Juan Perdomo, Alícia Molina-Andujar and Esteban Poch

46. Renal Protection and Nephritic Support for Cardiopulmonary Bypass

Kaan Kırali, Özge Altaş, Mustafa Emre Gürcü and Şefika Kılıç

47. Splanchnic Protection and Support for Cardiopulmonary Bypass

Paulo Roberto Barbosa Evora, Gabriel Bianco Giuliani, Cecilio Jacob and Patricia Martinez

48. Intestinal Protection and Enteric Support for Cardiopulmonary Bypass

Amer Harky, Kelly Wright and Naomi Melamed

49. Endocrinological Protection and Hormonal Support for Cardiopulmonary Bypass

Paulo Roberto Barbosa Evora, Gabriel Bianco Giuliani, Cecilio Jacob and Patricia Martinez

50. Vessels Injury in Cardiopulmonary Bypass

Assunta Fabozzo, Chiara Tessari, Giorgia Cibin and Gino Gerosa

51. Infectional Protection and Antimicrobial Support for Cardiopulmonary Bypass

Kaan Kırali, Yeşim Uygun Kızmaz, Pınar Atagün Güney and Nuray Çankaya

VOLUME II

Part VIII. Extra Corporeal Membranous Oxygenation (ECMO)

52. Extracorporeal Membrane Oxygenation (ECMO)

Kaan Kırali, Atakan Erkılınç, Serpil Gezer Taş and İsmail Yerli

53. Contraindications for ECMO

John Kyle Bohman, Misty Radosevich and Shihab Sugeir

54. Hemodynamic Evaluation of Cannulas for ECMO

Akif Undar, Krishna Patel, David Palanzo, Christoph Brehm and John L. Myers

55. ECG-Synchronized Pulsatility for ECMO

Akif Undar, Estelle Green, Orhun Davarci, Krishna Patel and Joseph B. Clark

56. Cardiac Protection and Management during ECMO

Kaan Kırali, Deniz Günay, Mehmet Aksüt, Sabit Sarıkaya and Hacı Aslan

57. Pulmonary Protection and Management during ECMO

Steven Keller

58. Hemorraghic Protection and Management during ECMO

Hanne Berg Ravn and Henrik Schmidt

59. Cerebral Protection and Management during ECMO

Mirko Belliato, Andrea Pellegrini and Roberto Veronesi Sr.

60. Renal Protection and Management during ECMO

Kaan Kırali, Murat Gücün, Aytaç Polat and Nazlı Kılıç

61. Gastrointestinal Protection and Management during ECMO

Paulo Roberto Barbosa Evora, Cecilio Jacob, Gabriel Bianco Giuliani and Patricia Martinez

62. Vascular Protection and Management during ECMO

Subhasis Chatterjee, Chibueze Onyemkpa, Zachary Pallister, Orlando Suero and Jayer Chung

63. Infection Protection and Management during ECMO

Nicolo Patroniti and Angelo Insorsi

64. Inflammatory Protection and Management during ECMO

Kiran Shekar, Elliott Theodrose Worku and Katrina K. Ki

Part IX. Special Situations for ECMO

65. Ethics and Quality Assurance for ECMO

Kollengode Ramanathan, Kiran Shekar and Ujwal Dhundi

66. Education and Training for ECMO

Melissa Brunsvold, Robert E Bulander Jr and Ahmad Abutaka

67. Nursing Care for ECMO

Jo-anne Fowles and Andrew Hadley-Brown

68. Transport and Retrieval for ECMO

Ahmed Labib and Guillaume Alinier

69. Weaning Strategies for ECMO and Awake ECMO

Wiebke Sommer and Gregor Warnecke

Part X. ECMO Support in Non-Cardiac Etiology

70. ECMO in Neonates and Infants

Denise Suttner

71. CRRT during ECMO in Neonates and Infants

Akif Undar, Lilly Su, Ryan M. Holcomb and John L. Myers

72. ECMO in Nonsurgical Lung Conditions

John Kyle Bohman, Juan Camilo Diaz Soto and Misty Radosevich

73. ECMO in Lung Surgery

Shahrokh Taghavi, Alberto Benazzo, Konrad Hötzenecker and Anders Andreasson

74. ECMO in Intracranial Surgery

Gevalin Srisooksai and Christoph N. Seubert

75. ECC/ECMO in Controlled Reperfusion of Whole Body (CARL)

Georg Trummer, Christoph Benk, Jan-Steffen Pooth, Sam Brixius and Friedhelm Beyersdorf

76. ECMO in Accidental Hypothermia

Kiran Shekar, Saikat Mitra, Kollengode Ramanathan and Justyna Swol

77. ECMO in Trauma

Akbarshakh Akhmerov and Danny Ramzy

78. ECMO in Pandemics

Cara Agerstrand, Briana Short, Philippe H. Lemaitre and Meaghan Flatley

79. ECMO in COVID-ARDS

Kaan Kırali, Adile Ece Altınay, Şirin Menekşe and Sibel Aydın

Part XI. ECMO Support in Non-Surgical Cardiac Etiology

80. ECMO for Challenging Percutaneous Intervention

Matthew Acton, Corbin E. Goerlich and Ahmet Kilic,

81. ECMO for End-stage Heart Failure

Ahmet Kilic, Corbin E. Goerlich and Matthew Acton

82. ECMO for Cardiogenic Shock

Ibrahim Akin, Michael Behnes and Tobias Schupp

83. ECMO for Cardiopulmonary Arrest (E-CPR)

Hanne Berg Ravn and Henrik Schmidt

Part XII. ECMO Support in Surgical Cardiac Etiology

84. ECMO for Postcardiotomy Syndrome in Adults

Alexis Edward Shafii and Bhalinder Dhaliwal

85. ECMO for Postcardiotomy Syndrome in Pediatrics

Katsuhide Maeda and Tracey R. Geoffrion

86. ECMO for post-LVAD Right Ventricular Failure

Jasmin Sarah Hanke, Güneş Doğan and Jan D. Schmitto

87. ECMO for Thoracic Transplantation

Leslie James, Deane E. Smith and Nader Moazami

Part XIII. Non-ECMO Artificial Life Support

88. Non-ECMO Artificial Circulatory Support Devices

Mevlut Çelik and Simon Maltais

89. Non-ECMO Artificial Respiratory Support Devices

Jung-Yien Chien, Ting-Yu Liao and Yih-Sharng Chen

90. Non-ECMO Artificial Circulatory Support for Postcardiotomy Syndrome

Kenneth K. Liao and Harveen Lamba

91. Non-ECMO Artificial Circulatory Support for Percutaneous Interventions

Gregory W. Serrao, Anoop Ninan Koshy and Samin Sharma

92. Non-ECMO Artificial Life Support for Thoracic Transplantation

Jae-Seung Jung and SeokJin Haam

Epilogue

Kaan Kırali