Deuterium Oxide and Deuteration in Biosciences

Dr. Chang-Hwei Chen is a biophysicist and professor emeritus of Biomedical Sciences at the School of Public Heath, University at Albany. He is currently a member of the Institute of Health and the Environment at the University at Albany.

Section I. Roles of regular and heavy water in biosciences

Overview: background and applications

Characteristics of deuterium oxide versus hydrogen oxide

Section II. Molecular interactions of deuterium versus hydrogen oxide

Deuterium bonding versus hydrogen bonding

Hydrophobic interaction in D2O versus H2O

Section III. Implications of deuterium oxide and deuteration in biological Systems

Deuterium oxide and deuteration effects on biomolecules

Effects of D2O and deuteration on biomembranes

Section IV. Applications of D2O and deuteration to biochemical reactions

Physical methods for investigating D2O and deuteration effects

Section V. Exploration of deuterium oxide and deuteration in health-related research

Living cells grown in deuterium oxide and deuteration

Deuterium oxide and deuteration effects on health issues

Section VI. Applications of deuterium oxide and deuteration to pharmacology

Deuterium oxide effects on thermostability of vaccines

Deuterium oxide and deuteration effects on pharmacology