Medical Microbiology and Infection at a Glance (eBook)

Stephen H. Gillespie is Professor of Medicine in the School of Medicine, University of St. Andrews, Fife, UK. Kathleen B. Bamford is a Consultant Medical Microbiologist at The Royal Cornwall Hospital, Cornwall, UK.

Biographies vii

Preface to the Fifth Edition ix

About the Companion Website xi

Part 1 Concepts 1

1 Microbial pathogens, classification and concepts 2

2 Innate and acquired immunity 4

3 The 'normal' flora in health and disease 6

4 Pathogenicity and pathogenesis of infectious disease 8

5 Making a microbiological diagnosis of infection 10

6 Antimicrobial therapy - principals and concepts 12

7 Antibacterial agents - pharmacology and modes of action 14

8 Antimicrobial use and stewardship 16

9 Emergence and detection of resistance 18

10 Sources and transmission of infection 20

11 Principles of infection control 22

12 Infection in the healthcare environment 24

13 Immunization 26

14 Emerging infections 28

15 High consequence infectious diseases and bioterrorism preparedness 30

Part 2 Bacteriology 33

16 Staphylococcus 34

17 Haemolytic streptococcal infections 36

18 Other Gram- positive cocci and the alpha- haemolytic streptococci 38

19 Streptococcus pneumoniae 40

20 Listeria, bacillus, non-diphtheria corynebacterium 42

21 Diphtheria, tetanus and pertussis 44

22 Mycobacterium tuberculosis 46

23 Non- tuberculous mycobacteria and leprosy 48

24 Clostridium 50

25 Non- sporing anaerobic infections 52

26 Neisseria and Moraxella 54

27 Small Gram- negative coccobacilli: Haemophilus, Brucella, Francisella, Yersinia and Bartonella 56

28 Pathogenicity of enteric Gram-negative bacteria 58

29 Enterobacteriaceae clinical syndromes 60

30 Vibrio, Campylobacter and Helicobacter 62

31 Environmental pathogens: Pseudomonas, Burkholderia, Legionella and Acinetobacter 64

32 Chlamydia, Mycoplasma and Rickettsia 66

33 Spiral bacteria 68

Part 3 Virology 71

34 Virus structure and classification 72

35 Antiviral therapy 74

36 Herpesviruses I 76

37 Herpesviruses II 78

38 DNA viruses: adenovirus, parvovirus and poxvirus 80

39 Measles, mumps and rubella 82

40 Influenza viruses 84

41 Parainfluenza and other respiratory viruses 86

42 Enterovirus and viruses that infect the gastrointestinal tract 88

43 Hepatitis viruses 90

44 Tropical, exotic or arbovirus infections 92

Part 4 Mycology 95

45 Yeast infections 96

46 Filamentous fungi 98

47 Antifungal drugs and antifungal therapy 100

Part 5 Parasitology 103

48 Intestinal protozoa 104

49 Malaria, leishmaniasis and trypanosomiasis 106

50 Intestinal helminths 108

51 Tissue helminths 110

Part 6 Systemic infection 113

52 Congenital and perinatal infections 114

53 HIV infection and AIDS 116

54 Pyrexia of unknown origin and puerperal sepsis 118

55 Sepsis 120

56 Endocarditis, myocarditis and pericarditis 122

57 Infections of the central nervous system 124

58 Acute respiratory tract infections 126

59 Chronic infections of the lung and hospital acquired pneumonia 128

60 Urinary and genital infections 130

61 Infections of the bones and joints 132

62 Bacterial diarrhoeal disease 134

63 Zoonoses 136

64 Infections in immunocompromised patients 138

65 Ocular infections 140

66 Infections of the skin and soft tissue 142

Index 144