Immunoinformatics of Cancers (eBook)

Immunoinformatics of Cancers: Practical Machine Learning Approaches Using R takes a bioinformatics approach to understanding and researching the immunological aspects of malignancies. It details biological and computational principles and the current applications of bioinformatic approaches in the study of human malignancies. Three sections cover the role of immunology in cancers and bioinformatics, including databases and tools, R programming and useful packages, and present the foundations of machine learning. The book then gives practical examples to illuminate the application of immunoinformatics to cancer, along with practical details on how computational and biological approaches can best be integrated.
This book provides readers with practical computational knowledge and techniques, including programming, and machine learning, enabling them to understand and pursue the immunological aspects of malignancies.

• Presents the knowledge researchers need to apply computational techniques to immunodeficiencies
• Provides the most practical material for bioinformatics approaches to the immunology of cancers
• Gives straightforward and efficient explanations of programming and machine learning approaches in R
• Includes details of the most useful databases, tools, programming packages and algorithms for immunoinformatics
• Illuminates clear explanations with practical examples of immunoinformatic approaches to cancer

Nima Rezaei is professor of clinical immunology at Tehran University of Medical Sciences (TUMS), vice dean of international affairs in the School of Medicine, and deputy president of Research Center for Immunodeficiencies. He received his PhD in clinical immunology and human genetics from the University of Sheffield in the UK after graduation in medicine (MD) from TUMS. He has written hundreds of papers and edited for leading book series and is the founding president of Universal Scientific Education and Research Network (USERN), where he is directing several interest groups such the Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA) and the Cancer Immunology Project (CIP). He is the Deputy President of the Research Center for Immunodeficiencies. He has presented more than 400 lectures/ posters in congresses and published more than 6700 articles and several books, and major reference works.

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Immunoinformatics of Cancers: Practical Machine Learning Approaches Using R takes a bioinformatics approach to understanding and researching the immunological aspects of malignancies. It details biological and computational principles and the current applications of bioinformatic approaches in the study of human malignancies. Three sections cover the role of immunology in cancers and bioinformatics, including databases and tools, R programming and useful packages, and present the foundations of machine learning. The book then gives practical examples to illuminate the application of immunoinformatics to cancer, along with practical details on how computational and biological approaches can best be integrated.This book provides readers with practical computational knowledge and techniques, including programming, and machine learning, enabling them to understand and pursue the immunological aspects of malignancies. Presents the knowledge researchers need to apply computational techniques to immunodeficiencies Provides the most practical material for bioinformatics approaches to the immunology of cancers Gives straightforward and efficient explanations of programming and machine learning approaches in R Includes details of the most useful databases, tools, programming packages and algorithms for immunoinformatics Illuminates clear explanations with practical examples of immunoinformatic approaches to cancer