Three Dimensional Human Organotypic Models for Biomedical Research

Fabio Bagnoli is discovery project leader of research & development programs at GSK. Research conducted by Fabio led to the filing of several patents as well as publications on various human pathogens published in important peer-reviewed journals. He has served as editor of several publications and is the coordinator of an industrial-academic effort on human organotypic models. He holds a PhD in Molecular and Cellular Microbiology from the University of Padova and conducted post-doctoral studies at Stanford University under the guidance of Dr. Stanley Falkow and Dr. Manuel Amieva.

Rino Rappuoli is Chief Scientist and Head External R&D at GSK Vaccines, based in Siena, Italy and Professor of Vaccinology at Imperial College, London. Prior positions: head of Vaccine R&D at Novartis, CSO of Chiron Corporation, head for R&D at Sclavo.

Introduction: Rationale of using skin models in research.- Skin anatomy (human and animals for experimental research).- In vivo skin models.- In vitro human skin models (Skin equivalents vs skin explants).- Human skin models for studying cutaneous infections.- Skin animal models for pharmacological research.- Human skin models for pharmacological research.- Human skin models for allergological research.- Human skin models for cancer research.- Human skin models for vaccine research.