Bone Metastasis and Molecular Mechanisms

1 Models of Breast Cancer Metastasis to Bone: Characterization of a Clinically Relevant Model.- 2 Quantitation of Bone Metastasis in Experimental Systems.- 3 Comparative Morphometric Study on Bone Remodeling in Human Specimens and in Experimental Models of Metastatic Bone Disease.- 4 Clinical Modalities for the Diagnosis, Characterization and Detection of Bone Metastases.- 5 Metastasis in the Bone Marrow Microenviroment.- 6 The Role of Tumor-Associated Macrophages in Metastasis-Associated Osteolysis.- 7 The Malignant Hierarchy in Multiple Myeloma: Relationships between Malignant Cells and Bone Disease.- 8 Angiogenesis and Lymphangiogenesis in Metastatic Bone Disease: A Matter of Networking.- 9 Prostate Cancer: Models for Developing Novel Therapeutic Approaches.- 10 Potential Therapeutic Targets for Bone Metastasis.- 11 OPG, RANK and RANKL in Bone Metastasis and Cancer-Associated Osteolysis.- 12 Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer.- 13 The Role of Bisphosphonates in Bone Metastasis.