Pancreatic Cancer: A Multidisciplinary Approach

Manoop S. Bhutani,MD FASGE,FACG,FACP,AGAF Walter H Wriston Distinguished Professor for Pancreatic Cancer Research Director of Endoscopic Research & Development Dept. of Gastroenterology,Hepatology and Nutrition UT MD Anderson Cancer Center, Houston,TX,USA  Matthew H.G. Katz, MD, FACS Lockton Distinguished Chair in Pancreatic Cancer Research Professor and Chair Department of Surgical Oncology The University of Texas MD Anderson Cancer Center Houston, TX USA  Anirban Maitra, MD Scientific Director, Sheikh Ahmed Bin Zayed Al Nahyan Center for Pancreatic Cancer Research Professor, Department of Pathology and Translational Molecular Pathology University of Texas MD Anderson Cancer Center Houston, TX USA   Joseph Herman MD, MSc, MSHCM* Director of Clinical Research Professor, Zucker School of Medicine at Hofstra/Northwell Vice Chair of Informatics, Department of Radiation Oncology Northwell Health Cancer Institute New Hyde Park, NY USA *Previously at UT MD Anderson Cancer Center at the time of conception of this work.   Robert A. Wolff, MD Sheikh Zayed Bin Sultan Al Nahyan Distinguished University Chair of Medical Oncology Professor, Department of Gastrointestinal Medical Oncology  University of Texas MD Anderson Cancer Center Houston, TX USA

1. Pancreatic Cancer at a Glance    

2. Risk Factors and Genetic Predisposition

3. Pancreatic Cancer and Diabetes Mellitus               

4. Pancreatic Cancer Screening         

I. Diagnosis and Staging of Pancreatic Cancer                                          

5. Imaging Evaluations: Pancreatic Protocol CT and MRI, PET-CT      

6. Laparoscopy      

7. Role of Gastroenterologists: Endoscopic Ultrasound (EUS), EUS-guided Biopsy

8 . Role of Ca 19-9 in Diagnosis/Staging and Management  

II. Management of Locally Advanced/ Metastatic Disease                                  

9. Medical Oncology           

10. Radiation Oncology        

III. Management of Resectable and Borderline Resectable Disease                                  

12. Medical Oncology           

13. Radiation Oncology        

IV. Endoscopic Management of Pancreatic Cancer Symptoms                                            

14. Jaundice/Biliary Obstruction: ERCP/EUS BD          

15. Gastric Outlet Obstruction: Antroduodenal Stenting, Venting PEG, EUS-guided Gastrojejunostomy

16. Pain Control: Celiac Plexus Neurolysis     

V. Emerging Paradigms in Pancreatic Cancer                                             

17. Minimally Invasive Surgical Approaches

19. Imaging Based Biomarkers for Pancreatic Cancer              

20. Liquid Biopsies in Pancreatic Cancer        

21. Molecular Profiling and Precision Medicine for Pancreatic Cancer              

22. The Prospects of Immunotherapy in Pancreatic Cancer   

23. Microbiome in Pancreatic Cancer             

24. Early Drug Development in Pancreatic Cancer

25. Mechanisms and Evidence on Pancreatic Cancer Prevention

26. Nutrition in Pancreatic Cancer    

27. Prioritizing the Patient Experience: Early Integration of Supportive/Palliative Care in Pancreatic Cancer Management   

28. Patient Reported Outcomes and Quality of Life  

29. Alternative/Integrative Medicine in Pancreatic Cancer