Genetic Polymorphism and Disease

Dr. Syed Sameer Aga is currently working as an Assistant Professor of Biochemistry in the Department of Basic Medical Sciences, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia. He is also serving as the Chairman of the Quality Assurance Unit in College of Medicine, KSAU-HS. Dr. Syed is a life-time member of many societies related to genetics, molecular biology and medical education like the Royal Society of Biology, Biochemical Society, Association of Clinical Biochemists of India, Society of Indian Academy of Medical Genetics, Middle East Molecular Biology Sources, Asian Council of Science Editors, and Saudi Society of Medical Education, etc. He is also serving as the Associate Editor in five Journals, Frontiers in Oncology – Molecular Biosciences section, BioMed Research International, Education Research International, World Journal of Biological Chemistry and Current Drug Metabolism. He also serves as a full time reviewer for various journals including European Journal of Cancer Prevention (Lippincott Williams & Wilkins), PLOS One & PLOS Genetics (Public Library of Science), World Journal of Gastroenterology (Baishideng Publishing), BMC Medical Genetics (BMC-Springer), Gene & Meta Gene (Elsevier Publishing), Bioscience Reports (Portland Press), Journal of Clinical Laboratory Analysis (John Wiley & Sons) and Tumor Biology (Sage Journals) etc. His research interests are focused on cancer biology and he has published more than ninety research and review articles in high repute journals with an h-index of 22 and authored ten books. Dr. Mujeeb Zafar Banday is presently working as a Senior Researcher and Lecturer in the Department of Biochemistry, Govt. Medical College, Srinagar. Dr. Banday has completed his Ph.D., M.Phil. and M.Sc. in Biochemistry from the University of Kashmir, J&K, India. He is serving as the review editor and associate reviewer for the journal, Frontiers in Oncology - Cancer Epidemiology and Prevention (Frontiers Group) and full time reviewer for various journals including Gene (Elsevier Publishing), Bioscience Reports (Portland Press), BioMed Research International (Hindawi Publishing) and Toxicology and Environmental Health Sciences Review (Springer Nature). He has authored more than twenty research and review articles and three books. Dr. Saniya Nissar is presently working as a Senior Researcher and Lecturer in the Department of Biochemistry, Govt. Medical College, Srinagar. She has completed her PhD, MPhil, and MSc in clinical biochemistry from the University of Kashmir, J&K, India. She works as free-lance scientific content writer with many scientific magazines. She has published more than thirty research and review articles and authored four books.

Table of Contents

1 Genetic Polymorphisms - Classification, Structure, Detection and Function

2 Clinical relevance of Pharmacogenomics a road to personalized medicine

3 Role of SNPs in diabetes susceptibility

4 Role of Single nucleotide polymorphisms in Asthma

5 Xenobiotic Gene polymorphism and their role in cancers

6 Association of MMP gene polymorphisms with cancer risk

7 Vitamin D receptor polymorphisms and diseases

8 Fatty Acid Metabolism Gene polymorphism in disease/cancer Susceptibility

9 Single Nucleotide Polymorphisms and Parkinson's Disease Susceptibility

10 Genetic Polymorphisms, role in drug metabolism and effect on Clinical Pharmacy

11 Role of Genetic polymorphisms in chronic inflammatory diseases

12 Single nucleotide polymorphism related computational-resources part I: Databases

13 Single nucleotide polymorphism related computational-resources part I: Alogrithms

14 Role of single nucleotide polymorphisms (SNPs) in common migraine

15 Role of Vitamin D SNPs in Cancer Susceptibility

16 Role of Genetic Polymorphisms in lipid metabolism pathways in modulating cancer promotion

17 Prostate cancer and genetic polymorphism

18 Role of Single Nucleotide Polymorphism of Cytochrome P450 Genes in Cancer Susceptibility

19 Role of Single Nucleotide Polymorphisms of Inflammatory molecules in susceptibility to Cardiovascular diseases (CVDs)

20 Role of Genetic Polymorphisms in the Etiopathogenesis of Esophageal Cancer

21 Cytokine polymorphism and their role in cancers

22 Gastric Cancer and genetic polymorphism in modulating the susceptibility

23 Cytokine Gene Polymorphisms & their Role in Autoimmune Diseases

24 Genomic disturbances associated with penile cancer and novel therapies

25 Role of Genetic Polymorphisms in Gastric Cancer Susceptibility