Hematology - Ronald Hoffman, Edward J. Benz, Sanford J. Shattil, Bruce Furie, Harvey Jay Cohen

Hematology

Basic Principles and Practice
Media-Kombination
2864 Seiten
2003 | 4th Revised edition
Churchill Livingstone
978-0-443-06662-7 (ISBN)
399,95 inkl. MwSt
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Reflects the growth of the field of haematology as an academic and clinical discipline. Including the 2-volume 4th edition, this e-dition covers both the basic scientific foundations of haematology and its clinical aspects. It provides practitioners with comprehensive information in haematology. It is suitable for practicing haematologists.
The fourth edition of this leading text reflects the new direction and growth of the field of haematology as an academic and clinical discipline. Edited and written by practitioners who are the leaders of the field, the book covers both the basic scientific foundations of haematology and its clinical aspects. It provides practitioners with the most comprehensive, authoritative, up-to-date information in haematology. The table of contents has been thoroughly revised with many new chapters added, reflecting the rapidly changing nature of the molecular and cellular areas of the specialty. This definitive resource is the one comprehensive book needed by every practicing haematologist. This e-dition includes the 2-volume 4th edition, plus access to website, where you'll find the fully searchable contents of the book, weekly updates to content, and much more!

Part I. MOLECULAR AND CELLULAR BASIS OF HEMATOLOGY Chapter 1:Anatomy and Physiology of the Gene Chapter 2:Genomic Approaches to the Study of Hematologic Science Chapter 3:Protein Synthesis, Processing, and Degradation Chapter 4:Protein Architecture: Relationship of Form and Function Chapter 5:Regulation of Cellular Response Chapter 6:Cell Adhesion Chapter 7:Control of Cell Division Chapter 8:Cell Death Chapter 9:Pharmacogenomics and Hematological Diseases Part II. IMMUNOLOGIC BASIS OF HEMATOLOGY Chapter 10:Overview and Compartmentalization of the Immune System Chapter 11:B-Cell Development Chapter 12:T-Cell and NK-Cell Immunity Chapter 13:Dendritic Cell Biology Chapter 14:Regulation of Activation of B and I Lymphocytes Chapter 15:Leukocyte Trafficking Chapter 16:Tolerance and Autoimmunity Part III. BIOLOGY OF STEM CELLS AND DISORDERS OF HEMATOPOIESIS Chapter 17:Stem Cell Model of Hematopoiesis Chapter 18:Bone Marrow Microenvironment Chapter 19:The Humeral Regulation of Hematopoiesis Chapter 20:Biology of Erythropoiesis, Erythroid Differentiation, and Maturation Chapter 21:Granulopoiesis and Monocytopoiesis Chapter 22:Thrombocytopoiesis Chapter 23:Thrombocytopenia Due to Decreased Platelet Production Chapter 24:Inherited Forms of Bone Marrow Failure Chapter 25:Aplastic Anemia Chapter 26:Paroxysmal Nocturnal Hemoglobinuria Chapter 27:Pure Red Cell Aplasia Part IV. RED BLOOD CELLS Chapter 28:Pathobiology of the Human Erythrocyte and Its Hemoglobins Chapter 29:Approach to Anemia in the Adult and Child Chapter 30:Anemia of Chronic Diseases Chapter 31:Pathology of Iron Metabolism Chapter 32:Disorders of Iron Metabolism: Iron Deficiency and Overload Chapter 33:Heme Biosynthesis and Its Disorders: Porphyrias and Sideroblastic Anemias Chapter 34:Megablastic Anemias Chapter 35:Thalassemia Syndromes Chapter 36:Pathology of Sickle Cell Disease Chapter 37:Sickle Cell Disease Chapter 38:Hemoglobin Variants Associated with Hemolytic Anemia, Altered Oxygen Affinity, and Methemoglobinemias Chapter 39:Red Cell Enzymopathies Chapter 40:Red Cell Membrane Disorders Chapter 41:Autoimmune Hemolytic Anemias Chapter 42:Extrinsic Nonimmune Hemolytic Anemias Part V. HOST DEFENSE AND ITS DISORDERS Chapter 43:Complement Biology and Immunoglobulin Chapter 44:Normal Phagocyte Structure and Function Chapter 45:Eosinophilia, Eosinophil-Associated Diseases, Chronic Eosinophil Leukemia, and the Hypereosinophilic Syndromes Chapter 46:Disorders of Phagocyte Function and Number Chapter 47:Disorders of Lymphocyte Function Chapter 48:Histiocytic Disorders Chapter 49:Lysosomal Storage Diseases: Perspective and Principles Chapter 50Infectious Mononucleosis and Other Epstein-Barr Virus-Associated Diseases Chapter 51:The Spleen and Its Disorders Chapter 52:Basophils, Mast Cells, and Systemic Mastocytosis Part VI. HEMATOLOGIC MALIGNANCIES Chapter 53:Conventional Cytogenetics and Molecular Cytogenetics in Hematological Malignancies Chapter 54:The Molecular Basis of Neoplasia Chapter 55:Pharmacology and Molecular Mechanisms of Antineoplastic Agents for Hematologic Malignancies Chapter 56:Radiation Therapy in the Treatment of Hematologic Malignancies Chapter 57:Clinical Use of Hematopoietic Growth Factors Chapter 58:Radioimmunotherapy for B-Cell and Non-Hodgkin Lymphoma Chapter 59:Pathobiology of Acute Myeloid Leukemia Chapter 60:Clinical Manifestations of Acute Myeloid Leukemia Chapter 61:Therapy for Acute Myeloid Leukemia Chapter 62:Acute Myeloid Leukemia in Children Chapter 63:Pathobiology of Acute Lymphoblastic Leukemia Chapter 64:Clinical Manifestations of Acute Lymphoblastic Leukemia Chapter 65:Treatment of Childhood Acute Lymphoblastic Leukemia Chapter 66:Acute Lymphoblastic Leukemia in Adults Chapter 67:Myelodysplastic Syndrome: Biology and Treatment Chapter 68:Polycythemia Vera Chapter 69:Chronic Myeloid Leukemia Chapter 70:Myelofibrosis with Myeloid Metaplasia Chapter 71:Essential Thrombocythemia Chapter 72:Myelodysplastic Syndromes and Myeloproliferative Syndromes in Children Chapter 73:Pathobiology of Non-Hodgkin Lymphomas Chapter 74:Patho-Biology of Hodgkin's Lymphoma Chapter 75:Hodgkin's Disease: Clinical Manifestations, Staging, and Therapy Chapter 76:The Pathologic Basis for the Classification of Non-Hodgkin Lymphomas Chapter 77:Clinical Manifestations, Staging, and Treatment of Non-Hodgkin Lymphoma Chapter 78:Malignant Lymphomas in Childhood Chapter 79:Chronic Lymphocytic Leukemia Chapter 80:Hairy Cell Leukemia Chapter 81:Cutaneous T-Cell Lymphomas Chapter 82:AIDS-Related Lymphomas Chapter 83:Multiple Myeloma and Other Plasma Cell Disorders Chapter 84:Immunoglobulin Light Chain Amyloidosis (Primary Amyloidosis, AL) Chapter 85:Atypical Immune Lymphoproliferations Chapter 86:Clinical Approaches to Infections in the Compromised Host Chapter 87:Nutritional Support of Patients with Hematologic Malignancies Chapter 88:Psychosocial Aspects of Hematologic Disorders Chapter 89:Pain Management and Antiemetic Therapy in Hematologic Disorders Chapter 90:Palliative Care Chapter 91:Indwelling Access Devices Chapter 92:Late Complications of Hematologic Diseases and Their Therapies Part VII. TRANSPLANTATION Chapter 93:Hematopoietic Stem Cell Transplantation for Acquired Nonmalignant Diseases and Myelodysplastic Syndrome Chapter 94:Hematopoietic Cell Transplant for Immune Deficiences and Genetic Diseases Chapter 95:Results of Allogeneic Hematopoietic Cell Transplant for Hematologic Malignancies Chapter 96:Autologous Transplant for Hematologic malignancies and Solio Tumors Chapter 97:Unrelated Donor Stem Cell Transplantation Therapy Anasetti Chapter 98:Umbilical Cord Blood Transplantation Chapter 99:Preparative Regimens for Hematopoietic Cell Transplantation Chapter 100:Graft-versus-Host Disease and Graft-versus-Leukemia Chapter 101:Graft Engineering to Enhance Engraftment, Reduce Graft-versus-Host Disease and Provide a Graft-versus-Tumor Effect Chapter 102:Gene Transfer for Hematologic Disorders Chapter 103:Experimental Cell Therapy Chapter 104:Complications After Hematopoietic Cell Transplantation Part VIII. HEMOSTASIS AND THROMBOSIS Chapter 105:Megakaryocyte and Platelet Structure Chapter 106:The Molecular Basis for Platelet Function Chapter 107:The Molecular Basis for Platelet Activation Chapter 108:The Blood Vessel Wall Chapter 109:Molecular Basis of Blood Coagulation Chapter 110:Molecular and Cellular Basis of Fibrinolysis Chapter 111:Regulatory Mechanisms in Hemostasis: Natural Anticoagulants Chapter 112:Clinical Evaluation of Hemorrhagic Disorders: Bleeding History and Differential Diagnosis of Pupura Chapter 113:Laboratory Evaluation of Hemostatic Disorders Chapter 114:Structure, Biology, and Genetics of Factor VIII Chapter 115:Biochemistry of Factor IX and Molecular Biology of Hemophilia B Chapter 116:Clinical Aspects and Therapy of Hemophilia Chapter 117:Inhibitors in Hemophilia Chapter 118:Other Clotting Factor Deficiencies Chapter 119:Disorders of Fibrinogen Chapter 120:Structure, Biology, and Genetics of von Willebrand Factor Chapter 121:von Willebrand Disease: Clinical Aspects and Therapy Chapter 122:Vitamin K: Metabolism and Disorders Chapter 123:Inhibitors of Blood Coagulation Chapter 124:Disseminated Intrvascular Coagulation Chapter 125:Hemostatic Defects Associated with Dysproteinemias Chapter 126:Disorders of Coagulation in the Neonate Chapter 127:Hypercoagulable States Chapter 128:Venous Thromboembolism Chapter 129:Arterial Thromboembolism Chapter 130:Anticoagulation and Thrombolytic Therapy Chapter 131:Immune Thrombocytopenic Purpura, Neonatal Alloimmune Thrombocytopenia, and Posttransfusion Purpura Chapter 132:Thrombotic Thrombocytopenic Purpura and the Hemolytic Uremic Syndrome Chapter 133:Thrombocytopenia Due to Platelet Destruction and Hypersplenism Chapter 134:Hereditary Disorders of Platelet Function Chapter 135:Acquired Disorders of Platelet Function Part IX. TRANSFUSION MEDICINE Chapter 136:Human Blood Group Anitgens and Antibodies - Part 1: Carbohydrate Determinants - Part 2: Protein Determinants Chapter 137:Human Platelet Antigens Chapter 138:Human Leukocyte Antigen (HLA) and Human Neutrophil Antigen (HNA) Systems Chapter 139:Principles of Red Blood Cell Transfusion Chapter 140:Principles of Platelet Transfusion Therapy Chapter 141:Principles of Neutrophil (Granulocyte) Transfusions Chapter 142:Transfusion of Plasma Derivatives: Fresh-Frozen Plasma, Cryoprecipitate, Albumin, and Immunoglobulins Chapter 143:Preparation of Plasma-Derived and Recombinant Human Plasma Proteins Chapter 144:Transfusion Therapy for Coagulation factor Deficiencies Chapter 145:Hemapheresis and Cellular Therapy Chapter 146:Practical Aspects of Stem Cell Collection Chapter 147:Transfusion Reactions Chapter 148:Transfusion-Transmitted Diseases Chapter 149:Transfusion Medicine in Hematopoietic Stem Cell and Solid Organ Transplantation Chapter 150:Red Blood Cell Substitutes Part X. CONSULTATIVE HEMATOLOGY Chapter 151:Hematologic Manifestations of Systemic Disease: Liver and Renal Disease Chapter 152:Hematologic Manifestations of Systemic Disease: Infection, Chronic Inflammation, and Cancer Chapter 153:Hematologic Manifestations of AIDS Chapter 154:Hematologic Problems in the Surgical Patient: Bleeding and Thrombosis Chapter 155:Hematologic Aspects of Pregnancy Chapter 156:Hematologic Manifestations of Childhood Illness Part XI. SPECIAL TESTS AND PROCEDURES Chapter 157:Bone Marrow Examination Chapter 158:Automated Analysis of Blood Cells Chapter 159:Laboratory Detection of Hemoglobinopathies and Thalassemias Chapter 160:Antenatal Diagnosis of Hematologic Disorders Chapter 161:Use of Molecular Techniques in the Analysis of Hematologic Diseases Chapter 162: Molecular Imaging in Hematology Appendix - Normal Blood Values: Selected Reference Values for Neonatal, Pediatric, and Adult Populations

Erscheint lt. Verlag 5.12.2003
Zusatzinfo ill
Verlagsort London
Sprache englisch
Maße 216 x 276 mm
Gewicht 5950 g
Themenwelt Medizinische Fachgebiete Innere Medizin Hämatologie
ISBN-10 0-443-06662-0 / 0443066620
ISBN-13 978-0-443-06662-7 / 9780443066627
Zustand Neuware
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