Essentials of Medical Biochemistry

Chung-Eun Ha is an Associate Professor in the department of Native Hawaiian Healthat the John A. Burns School of Medicine, University of Hawaii at Manoa. Since 2001,he has been teaching medical biochemistry to students who come from disadvantagedbackgrounds. He is also actively involved in the various aspects of molecular biologyand biochemical research in the field of clinical medicine. N. V. Bhagavan is an Emeritus Professor in the department of Anatomy, Biochemistry,and Physiology at the John A. Burns School of Medicine, University of Hawaii at Manoa.An active professor, researcher, and teacher, he has many years of experience in boththe instruction and practice of clinical biochemistry.

1. The Human Organism: Organ Systems, Cells, Organelles, and Our Microbiota 2. Water, Acids, Bases, and Buffers 3. Amino Acids 4. Three-Dimensional Structure of Proteins and Disorders of Protein Misfolding 5. Energetics of Biological Systems, Enzymes and Enzyme Regulation 6. Clinical Enzymology and Biomarkers of Tissue Injury 7. Simple Carbohydrates 8. Heteropolysaccharides: Glycoconjugates, Glycoproteins, and Glycolipids 9. Connective Tissue: Fibrous and Nonfibrous Proteins and Proteoglycans 10. Gastrointestinal Digestion and Absorption 11. Carbohydrate Metabolism I: Glycolysis and the Tricarboxylic Acid Cycle 12. Electron Transport Chain, Oxidative Phosphorylation, and Other Oxygen-Consuming Systems 13. Carbohydrate Metabolism II: Gluconeogenesis, Glycogen Synthesis and Breakdown, and Alternative Pathways 14. Protein and Amino Acid Metabolism 15. Lipids I: Fatty Acids and Eicosanoids 16. Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol 17. Lipids III: Plasma Lipoproteins 18. Contractile Systems 19. Perturbations of Energy Metabolism: Obesity and Diabetes Mellitus 20. Structure and Properties of DNA 21. DNA Replication, Repair, and Mutagenesis 22. RNA and Protein Synthesis 23. Regulation of Gene Expression 24. Nucleotide Metabolism 25. Hemoglobin and Metabolism of Iron & Heme 26. Endocrine Metabolism I: Introduction and Signal Transduction 27. Endocrine Metabolism II: Hypothalamus and Pituitary 28. Endocrine Metabolism III: Adrenal Glands 29. Endocrine Metabolism IV: Thyroid Gland 30. Endocrine Metabolism V: Reproductive System 31. Immunology 32. Biochemistry of Hemostasis 33. Mineral Metabolism 34. Vitamin Metabolism 35. Drug Metabolism