Molecular Exercise Physiology

Adam P. Sharples, PhD, is a Professor of Molecular Physiology and Epigenetics at the Norwegian School of Sport Sciences (NiH), Olso, Norway; an institute ranked 2nd (out of 300+) in the world for sport and exercise sciences. He investigates the underlying cellular, molecular and epigenetic mechanisms of muscle growth (hypertrophy) and wasting (atrophy) using both cell modelling and whole-body approaches. His work first demonstrated that human muscle possesses an "epigenetic memory" of exercise. He used to play professional Rugby League in the UK. James P. Morton, PhD, is a Professor of Exercise Metabolism at Liverpool John Moores University (LJMU). His research evaluates the impact of nutrient availability on muscle metabolism during exercise and the molecular regulation of skeletal muscle adaptations to exercise training. James has also worked in a number of performance related roles across both high-performance sport and industry, working with some of the world’s most high profile athletes, sports teams and institutions. Henning Wackerhage, PhD, is a Professor and Molecular Exercise Physiologist. He is specifically interested in the molecular mechanisms by which exercise improves our fitness and health, particularly the role of the so-called Hippo proteins in skeletal muscle and the association between the proteome, metabolome, athletic performance, disease and ageing.

1. Introduction to molecular exercise physiology

2. Methods in molecular exercise physiology

3. Genetics and exercise: an introduction

4. Genetics of muscle mass and strength

5. Genetics of endurance

6. Epigenetics of exercise

7. Signal transduction and exercise

8. Molecular adaptation to resistance exercise

9. Molecular adaptations to endurance exercise and skeletal muscle fibre plasticity

10. Molecular sport nutrition

11. Altitude, temperature, circadiun rhythms and exercise

12. Cancer and exercise

13. Satellite cells and exercise