Modern ART in the 2000's: Andrology in the Nineties

Preface. Basic principles of evidence based medicine: from cookery to science: the postcoital test as an example. Intrauterine insemination for male subfertility. The value of GIFT procedures in assisted reproduction. In vitro fertilization (IVF) or gamete intrafallopian transfer (GIFT): which is the preferred method?. Role of sperm function test in subfertility treatment strategies. WHO guidelines for the interpretation of common semen parameters. Pitfalls of evidence based medicine in andrology and assisted reproduction. Total quality management and the clinical andrology laboratory essential partners. Methodological differences in sperm morphology assessments. Value and reliability of casa systems. Basic semen analysis courses: experience in Scandinavia. Basic semen analysis courses: experience in The Netherlands. Genetic aspects and ICSI: an update on non-Y-chromosomal genetic defects. Inheritance of mitochondrial DNA and its implications. The role of sperm centrosome during human fertilization and embryonic development: implications for ICSI and other sophisticated A.R.T. strategies. Intracytoplasmic sperm injection with ultrastructurally abnormal spermatozoa. Role of cytokines and other growth factors on sperm function. Reliability of methods for assessing the fertilizing capacity of human spermatozoa. Maturation arrest in spermatogenesis. The cell biology of the fertilizing spermatozoon. Index.