Biology of Negative Strand RNA Viruses: The Power of Reverse Genetics

Biology of Negative Strand RNA Viruses: The Power of Reverse Genetics

Buch | Hardcover
IX, 350 Seiten
2004 | 2004
Springer Berlin (Verlag)
978-3-540-40661-7 (ISBN)
213,99 inkl. MwSt

Negative-strand RNA viruses, so named because of the polarity of their genomic RNA to mRNA, include important human and non-human pathogens. This volume covers major advances in reverse genetics techniques over the past decade, state-of-the-art basic science and the clinical implications of experimental findings. This should rekindle interest in negative-strand RNA viruses among readers, including those in other disciplines, leading to further progress in understanding these important viruses and in developing effective measures of control.

List of Contents.- Reverse Genetics of Mononegavirales.- Reverse Genetics Systems for the Generation of Segmented Negative-Sense RNA Viruses Entirely from Cloned cDNA.- Transcription and Replication of Nonsegmented Negative-Strand RNA Viruses.- Orthomyxovirus Replication, Transcription, and Polyadenylation.- Escaping from the Cell: Assembly and Budding of Negative-Strand RNA Viruses.- Accessory Genes of the Paramyxoviridae, a Large Family of Nonsegmented Negative-Strand RNA Viruses, as a Focus of Active Investigation by Reverse Genetics.- Identification and Characterization of Viral Antagonists of Type I Interferon in Negative-Strand RNA Viruses.- Toward Novel Vaccines and Therapies Based on Negative-Strand RNA Viruses.- Influenza Vaccines Generated by Reverse Genetics.

Erscheint lt. Verlag 7.5.2004
Reihe/Serie Current Topics in Microbiology and Immunology
Mitarbeit Gast Herausgeber: Yoshihiro Kawaoka
Zusatzinfo IX, 350 p. 27 illus., 3 illus. in color.
Verlagsort Berlin
Sprache englisch
Maße 155 x 235 mm
Gewicht 620 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Schlagworte genes • Genetics • Interferon • Negative Strand RNA Viruses • Paramyxoviridae • Reverse Genetics • RNA • RNS (Ribonukleinsäure) • transcription • Vaccine • Virologie • Virus
ISBN-10 3-540-40661-1 / 3540406611
ISBN-13 978-3-540-40661-7 / 9783540406617
Zustand Neuware
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